Antibiotics resistance profile of escherichia coli isolated from apparently healthy domestic livestock
Table Of Contents
Chapter ONE
INTRODUCTION
- 1.1Introduction
- 1.2Background of study
- 1.3Problem Statement
- 1.4Objective of study
- 1.5Limitation of study
- 1.6Scope of study
- 1.7Significance of study
- 1.8Structure of the research
- 1.9Definition of terms
Chapter TWO
LITERATURE REVIEW
- 2.1Overview of Antibiotics
- 2.2Antibiotics Resistance Mechanisms
- 2.3Factors Contributing to Antibiotics Resistance
- 2.4Impact of Antibiotics Resistance on Public Health
- 2.5Antibiotics Usage in Livestock
- 2.6Antibiotics Resistance in Escherichia coli
- 2.7Previous Studies on Antibiotics Resistance in Livestock
- 2.8Strategies to Combat Antibiotics Resistance
- 2.9Regulations on Antibiotics Use in Livestock
- 2.10Future Directions in Antibiotics Resistance Research
Chapter THREE
RESEARCH METHODOLOGY
- 3.1Research Design
- 3.2Sampling Techniques
- 3.3Data Collection Methods
- 3.4Data Analysis Procedures
- 3.5Ethical Considerations
- 3.6Research Validity and Reliability
- 3.7Limitations of the Methodology
- 3.8Research Instrumentation
Chapter FOUR
DATA PRESENTATION AND ANALYSIS
- 4.1Data Presentation and Analysis
- 4.2Antibiotics Resistance Profile of Escherichia coli in Livestock
- 4.3Comparison of Antibiotics Resistance Patterns
- 4.4Factors Influencing Antibiotics Resistance
- 4.5Discussion on Antibiotics Resistance Trends
- 4.6Implications for Livestock Health
- 4.7Recommendations for Future Interventions
- 4.8Areas for Further Research
Chapter FIVE
SUMMARY, CONCLUSION AND RECOMMENDATIONS
- 5.1Summary of Findings
- 5.2Conclusions drawn from the Research
- 5.3Implications for Livestock Industry
- 5.4Contribution to Scientific Knowledge
- 5.5Recommendations for Policy and Practice
Thesis Abstract
This study was conducted to determine the antibiotic resistance profile of Escherichial Coli isolate from apparently healthy domestic livestock viz cow, goats and chicken from Osun State Nigeria. E. Coli was isolated using Eosin methylene Blue Agar (EMB) and identified by conventional microbiological technique. The isolate were tested against 14 antibiotics using the disc diffusion method. A total of 42 different antibiotics resistance profile were observed with each isolate showing resistance to at least four or more drugs tested. Generally, the E. coli isolates showed resistance rates of 93.8% to Ampicilin; 15.3% to Chloramphenicol, 52.7% to cloxacillin, 74.3% Erythromycin, 20.9% to Gentamicin, 53.8% to Penicillin, 17.7% to Streptomycin, 67.3% to Tetracyclin, 21.1% to Ceftazidine 70.7% to Cefuroxine, 20.5% to Cefixine, 28.8% to Ofloxacine, 58.6% to Augmentin, 27.2% to Nitorfurantion 27.3% to Ciprofloxacin. Statistical analysis showed that average number of resistance phenotypes per isolate was significantly higher for cow compared with poultry. A significant public health concern observed in this study is that multi drug resistant commensal E. Coli strains may constitute a potential reservoir of resistance genes that could be transferred to pathogenic bacteria.
Thesis Overview
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