Chapter ONE

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Chemopreventive Effects
2.2 Balanite Aegyptica Supplement Literature Review
2.3 Ziziphus Spina-Christy Supplement Literature Review
2.4 N-Methyl-N-Nitrosourea Induced Colon Carcinogenesis Review
2.5 Mechanisms of Colon Cancer Development
2.6 Previous Studies on Chemopreventive Effects
2.7 Animal Models in Chemoprevention Research
2.8 Clinical Trials on Chemopreventive Agents
2.9 Challenges in Chemoprevention Research
2.10 Future Directions in Chemoprevention Studies

Chapter THREE

3.1 Research Methodology Overview
3.2 Selection of Animal Model
3.3 Preparation and Administration of Supplements
3.4 Induction of Colon Carcinogenesis
3.5 Monitoring and Assessment of Carcinogenesis
3.6 Data Collection and Analysis Methods
3.7 Statistical Analysis Techniques
3.8 Ethical Considerations in Animal Studies

Chapter FOUR

4.1 Analysis of Chemopreventive Effects of Balanite Aegyptica Supplement
4.2 Analysis of Chemopreventive Effects of Ziziphus Spina-Christy Supplement
4.3 Comparison of Effects between Supplements
4.4 Histological Examination of Colon Tissues
4.5 Molecular Pathways Involved in Chemoprevention
4.6 Discussion on Potential Mechanisms of Action
4.7 Comparison with Previous Studies
4.8 Implications for Future Research

Chapter FIVE

5.1 Conclusion and Summary
5.2 Key Findings Recap
5.3 Contributions to the Field
5.4 Limitations and Future Directions
5.5 Recommendations for Further Studies