Home / Biochemistry / Estrogen receptor β and breast cancer

Estrogen receptor β and breast cancer

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Estrogen Receptor β
2.2 Role of Estrogen Receptor β in Breast Cancer
2.3 Gene Expression Regulation by Estrogen Receptor β
2.4 Cellular Signaling Pathways Involving Estrogen Receptor β
2.5 Therapeutic Targeting of Estrogen Receptor β in Breast Cancer
2.6 Clinical Implications of Estrogen Receptor β in Breast Cancer
2.7 Studies on Estrogen Receptor β and Breast Cancer
2.8 Emerging Research and Future Directions
2.9 Comparative Studies with Other Receptors
2.10 Summary of Literature Review

Chapter THREE

3.1 Research Design and Methodology
3.2 Selection of Sample Population
3.3 Data Collection Techniques
3.4 Data Analysis Methods
3.5 Experimental Procedures
3.6 Ethical Considerations
3.7 Validation of Research Instruments
3.8 Statistical Tools and Software Used

Chapter FOUR

4.1 Overview of Research Findings
4.2 Estrogen Receptor β Expression in Breast Cancer Patients
4.3 Correlation between Estrogen Receptor β Levels and Disease Progression
4.4 Response to Estrogen Receptor β Targeted Therapy
4.5 Impact of Estrogen Receptor β Mutations on Treatment Outcomes
4.6 Comparison with Estrogen Receptor α in Breast Cancer
4.7 Discussion on Conflicting Studies
4.8 Implications of Findings on Clinical Practice

Chapter FIVE

5.1 Conclusion and Summary
5.2 Key Findings Recapitulation
5.3 Research Objectives Achievement
5.4 Contributions to Existing Knowledge
5.5 Recommendations for Future Research

Thesis Abstract

Despite the primary role of estrogen receptor α (ERα) in mediating the effects of estrogen in malignant breast and as therapeutic target, the development of endocrine-resistant and metastatic phenotypes indicates the complexity of the mechanisms that regulate hormone signaling in the disease. The discovery of ERβ and its functional characterization has improved our understanding about the mechanism of estrogen receptor action, the regulation of estrogen signaling in breast tumors, and their response to therapy. The progressive decline of ERβ in pro-invasive lesions and invasive tumors points toward a role as suppressor of both tumorigenesis and progression in breast cancer. The antiproliferative and anti-invasive effects of the receptor and its agonists in preclinical models of breast cancer support these roles and delineate the mechanisms of action. The association of ERβ with clinical outcome proposes the potential use of the receptor as prognostic marker and its agonists in chemoprevention and therapeutic strategies for resistant and metastatic disease.

Thesis Overview

Blazingprojects Mobile App

📚 Over 50,000 Research Thesis
📱 100% Offline: No internet needed
📝 Over 98 Departments
🔍 Thesis-to-Journal Publication
🎓 Undergraduate/Postgraduate Thesis
📥 Instant Whatsapp/Email Delivery

Blazingprojects App

Related Research

Biochemistry. 4 min read

Exploring the Role of Gut Microbiota in Human Health and Disease...

The project titled "Exploring the Role of Gut Microbiota in Human Health and Disease" aims to investigate the intricate relationship between gut micro...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Investigating the role of microRNAs in regulating gene expression in cancer cells....

The project "Investigating the role of microRNAs in regulating gene expression in cancer cells" aims to delve into the intricate mechanisms by which m...

BP
Blazingprojects
Read more →
Biochemistry. 3 min read

Exploring the Role of Epigenetics in Cancer Development and Treatment...

The project titled "Exploring the Role of Epigenetics in Cancer Development and Treatment" focuses on investigating the intricate relationship between...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Analysis of the role of microRNAs in cancer progression...

The project titled "Analysis of the role of microRNAs in cancer progression" aims to investigate the intricate role of microRNAs in the progression of...

BP
Blazingprojects
Read more →
Biochemistry. 4 min read

Investigating the role of microRNAs in regulating gene expression in cancer cells....

**Research Overview: Investigating the Role of microRNAs in Regulating Gene Expression in Cancer Cells** Cancer is a complex disease characterized by uncontrol...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Exploring the role of microRNAs in regulating gene expression in cancer cells...

The project titled "Exploring the role of microRNAs in regulating gene expression in cancer cells" aims to investigate the intricate mechanisms by whi...

BP
Blazingprojects
Read more →
Biochemistry. 4 min read

Exploring the Role of MicroRNAs in Cancer Progression: Mechanisms and Therapeutic Po...

The project titled "Exploring the Role of MicroRNAs in Cancer Progression: Mechanisms and Therapeutic Potential" aims to investigate the intricate inv...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Exploring the role of microRNAs in cancer progression and potential therapeutic appl...

The project titled "Exploring the role of microRNAs in cancer progression and potential therapeutic applications" aims to investigate the intricate in...

BP
Blazingprojects
Read more →
Biochemistry. 3 min read

Exploring the role of gut microbiota in metabolic diseases...

The project titled "Exploring the role of gut microbiota in metabolic diseases" aims to investigate the intricate relationship between gut microbiota ...

BP
Blazingprojects
Read more →
WhatsApp Click here to chat with us