Thesis Abstract

Abstract
The aim of this study was to investigate the effects of various dietary supplements on lipid metabolism in rats. Lipid metabolism plays a crucial role in maintaining overall health, and imbalances in this process can lead to various metabolic disorders. In this research, a total of 60 rats were divided into six groups, each receiving a different dietary supplement Group A (control group with standard diet), Group B (Omega-3 fatty acids), Group C (Green tea extract), Group D (Vitamin E), Group E (Coenzyme Q10), and Group F (Acai berry extract). The rats were monitored over a period of 8 weeks to assess changes in lipid metabolism parameters, including serum lipid levels, liver function markers, and adipose tissue characteristics. The results showed that rats supplemented with Omega-3 fatty acids exhibited a significant decrease in total cholesterol and triglyceride levels compared to the control group. Green tea extract supplementation led to a reduction in LDL cholesterol levels and an increase in HDL cholesterol levels. Rats supplemented with Vitamin E showed improved liver function markers, while Coenzyme Q10 supplementation resulted in decreased adipose tissue mass. Acai berry extract supplementation showed a significant decrease in overall lipid accumulation in the liver. Overall, this study provides valuable insights into the potential benefits of different dietary supplements on lipid metabolism in rats. Understanding the effects of these supplements on lipid metabolism can have implications for the development of novel therapeutic strategies for managing metabolic disorders in humans. Further research is warranted to elucidate the underlying mechanisms of action and to explore the long-term effects of these dietary supplements on lipid metabolism.

Thesis Overview

The research project titled "Investigating the effects of different dietary supplements on lipid metabolism in rats" aims to explore how various dietary supplements impact lipid metabolism in rat models. Lipid metabolism plays a crucial role in maintaining overall health, as it involves the breakdown, utilization, and storage of fats in the body. Understanding how different dietary supplements influence this process can provide valuable insights into potential interventions for metabolic disorders and related health conditions. The project will involve administering different dietary supplements to groups of rats and analyzing their effects on lipid metabolism. By measuring parameters such as lipid levels in blood, liver, and adipose tissue, as well as gene expression related to lipid metabolism, the study aims to elucidate the mechanisms through which these supplements exert their effects. The research will also investigate the potential benefits or adverse effects of these supplements on overall health and metabolic function in the rat models. Through this comprehensive investigation, the project seeks to contribute to the existing body of knowledge on the relationship between dietary supplements and lipid metabolism. The findings of this research could have implications for developing targeted interventions or dietary recommendations to optimize lipid metabolism and prevent or manage metabolic disorders in humans. In summary, this project aims to shed light on the impact of dietary supplements on lipid metabolism in rats, with the ultimate goal of advancing our understanding of how these supplements can influence metabolic health. By unraveling the complex interactions between dietary components and lipid metabolism, this research has the potential to inform future strategies for promoting metabolic wellness and improving overall health outcomes.