Thesis Abstract

Abstract
Oxidative stress is a key factor in the development and progression of cancer, leading to DNA damage, cell proliferation, and tumor growth. Antioxidants have been studied for their potential in reducing oxidative stress and inhibiting cancer cell growth. This thesis investigates the effects of different types of antioxidants on oxidative stress in cancer cells. The study aims to evaluate the efficacy of various antioxidants in mitigating oxidative stress and their impact on cancer cell viability. Chapter 1 provides an introduction to the research topic, outlining the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definitions of key terms. The literature review in Chapter 2 examines previous research on antioxidants and oxidative stress in cancer cells, highlighting the potential mechanisms of action and outcomes of antioxidant treatment. Chapter 3 details the research methodology, including the selection of cancer cell lines, antioxidant compounds, experimental design, cell culture techniques, oxidative stress assays, and data analysis methods. The study design incorporates multiple antioxidants to assess their comparative effects on oxidative stress levels and cancer cell viability. In Chapter 4, the findings of the study are presented and discussed in detail. The results demonstrate varying degrees of antioxidant efficacy in reducing oxidative stress markers and inhibiting cancer cell proliferation. The discussion explores the implications of these findings in the context of cancer treatment and the potential for antioxidant therapy to complement existing cancer therapies. Finally, Chapter 5 provides a conclusion and summary of the research findings. The study confirms the importance of antioxidants in modulating oxidative stress in cancer cells and suggests potential avenues for further research in this area. The thesis contributes to the growing body of knowledge on the role of antioxidants in cancer biology and highlights the therapeutic potential of antioxidant compounds in cancer treatment. Overall, this research provides valuable insights into the effects of different types of antioxidants on oxidative stress in cancer cells, offering new perspectives on the development of targeted therapies for cancer treatment.

Thesis Overview

The project titled "Investigating the effects of different types of antioxidants on oxidative stress in cancer cells" aims to explore the potential impact of various antioxidants on oxidative stress within cancer cells. Oxidative stress, characterized by an imbalance between reactive oxygen species (ROS) production and the antioxidant defense system, plays a crucial role in cancer progression and development. Antioxidants are known for their ability to neutralize ROS and protect cells from oxidative damage, making them potential candidates for cancer therapy. The research will involve investigating different types of antioxidants, such as vitamins C and E, polyphenols, and flavonoids, to determine their effectiveness in mitigating oxidative stress in cancer cells. By conducting in vitro experiments utilizing cancer cell lines exposed to oxidative stress inducers, the study aims to evaluate the impact of antioxidants on ROS levels, cell viability, and oxidative damage markers. Furthermore, the project will delve into the underlying mechanisms through which antioxidants exert their protective effects against oxidative stress in cancer cells. This includes exploring antioxidant enzyme activity, gene expression profiles related to oxidative stress response, and signaling pathways involved in antioxidant-mediated cellular protection. The findings of this research have the potential to contribute valuable insights into the role of antioxidants in combating oxidative stress in cancer cells and may pave the way for the development of novel antioxidant-based therapeutic strategies for cancer treatment. Ultimately, the project aspires to enhance our understanding of the intricate interplay between antioxidants and oxidative stress in the context of cancer biology, offering new perspectives for advancing cancer therapy and improving patient outcomes.