Thesis Abstract

Abstract
MicroRNAs (miRNAs) are small non-coding RNA molecules that play critical roles in regulating gene expression and have been implicated in various physiological and pathological processes, including cancer progression. This thesis aims to explore the role of miRNAs in cancer progression and their therapeutic potential. The study begins with a comprehensive review of the literature on miRNAs in cancer, highlighting their involvement in key signaling pathways and processes associated with tumorigenesis. The research methodology section outlines the experimental approaches used to investigate the expression profiles of specific miRNAs in different cancer types and their functional effects on cancer cell behavior. The findings from these experiments are discussed in detail in the results section, which includes the identification of specific miRNAs that are dysregulated in cancer cells and their impact on cellular processes such as proliferation, migration, and invasion. The discussion section delves into the implications of these findings for understanding the molecular mechanisms underlying cancer progression and the potential for miRNAs as therapeutic targets. The study concludes with a summary of the key findings and their significance in the context of cancer biology and therapy. Overall, this thesis provides valuable insights into the role of miRNAs in cancer progression and highlights their potential as targets for novel therapeutic interventions. Further research in this area holds promise for the development of more effective and personalized cancer treatments aimed at improving patient outcomes.

Thesis Overview

The research project titled "Exploring the Role of MicroRNAs in Cancer Progression and Therapeutic Potential" aims to investigate the intricate relationship between MicroRNAs (miRNAs) and cancer progression, with a focus on their potential therapeutic applications. This study is motivated by the growing interest in miRNAs as key regulators of gene expression and their emerging role in cancer biology. The project will begin with a comprehensive review of the current literature on miRNAs and their involvement in cancer development and progression. This literature review will explore the mechanisms by which miRNAs contribute to cancer pathogenesis, including their ability to regulate oncogenes and tumor suppressor genes. Furthermore, it will examine the diagnostic and prognostic potential of miRNAs in various types of cancer. Following the literature review, the research methodology will be outlined, detailing the experimental approaches and techniques that will be employed to investigate the specific roles of miRNAs in cancer progression. This will include the collection and analysis of biological samples, such as tumor tissues and blood samples, to assess the expression levels of key miRNAs in cancer patients. The findings of this study will be discussed in detail in the subsequent chapter, highlighting the key miRNAs that are dysregulated in cancer and their potential as therapeutic targets. The results of this research will provide valuable insights into the molecular mechanisms underlying cancer progression and may lead to the development of novel miRNA-based therapies for cancer treatment. In conclusion, this research project will contribute to our understanding of the role of miRNAs in cancer progression and their therapeutic potential. By elucidating the complex interplay between miRNAs and cancer biology, this study has the potential to pave the way for the development of innovative strategies for cancer diagnosis, prognosis, and treatment.