Thesis Abstract

Abstract
Cancer remains a pressing global health concern, with the need for innovative research to advance our understanding of its complex mechanisms and potential treatment options. In recent years, microRNAs have emerged as key players in cancer development and progression, with their dysregulation implicated in various types of cancer. This thesis aims to investigate the role of microRNAs in cancer development and progression, shedding light on their potential as diagnostic markers and therapeutic targets. The introduction sets the stage by providing an overview of cancer as a multifaceted disease and introducing the significance of microRNAs in cancer biology. The background of the study delves into the molecular mechanisms underlying microRNA function and dysregulation in cancer, highlighting their role in regulating gene expression and signaling pathways. The problem statement emphasizes the need for in-depth research on the specific microRNAs involved in different types of cancer and their impact on tumor growth and metastasis. The objectives of the study are outlined to guide the research process towards identifying key microRNAs associated with cancer development and progression. Limitations of the study are acknowledged, including challenges related to sample availability, data analysis, and the dynamic nature of microRNA expression patterns. The scope of the study is defined in terms of the specific cancer types and microRNAs to be investigated, providing a clear focus for the research. The significance of the study lies in its potential to contribute to the field of cancer research by uncovering novel insights into the role of microRNAs in driving tumor growth and metastasis. The structure of the thesis is outlined to provide a roadmap for the reader, guiding them through the various chapters and sections of the research. Chapter two presents a comprehensive literature review, exploring existing studies on microRNAs in different types of cancer and their implications for diagnosis and treatment. The research methodology in chapter three details the experimental approach, sample collection, data analysis methods, and statistical techniques employed in the study. Chapter four presents the findings of the research, discussing the identified microRNAs associated with cancer development and progression, their target genes, and potential mechanisms of action. The implications of these findings for cancer diagnosis, prognosis, and therapy are explored in detail. Finally, chapter five offers a conclusion and summary of the thesis, summarizing the key findings, discussing their implications for cancer research and clinical practice, and suggesting future directions for further investigation. Overall, this thesis contributes to our understanding of the role of microRNAs in cancer and highlights their potential as valuable targets for precision medicine approaches in oncology. Keywords Cancer, microRNAs, development, progression, diagnosis, therapy, precision medicine.

Thesis Overview