1. Introduction
1.1 Background
1.2 Objectives
2. Drug Transporters: An Overview
2.1 Classification of Drug Transporters
2.2 Function and Mechanisms of Drug Transport
2.3 Regulation of Drug Transporters
3. Drug Transporters and Pharmacokinetics
3.1 Absorption and Distribution
3.2 Elimination and Metabolism
3.3 Drug-Drug Interactions
4. Drug Transporters and Pharmacodynamics
4.1 Target Site Delivery
4.2 Cellular Uptake and Efflux
4.3 Drug Resistance
5. Techniques for Studying Drug Transporters
5.1 In Vitro Assays
5.2 In Vivo Imaging
5.3 Genetic Approaches
Drug transporters play a crucial role in the absorption, distribution, and elimination of drugs in the body. This project aims to investigate the biochemistry of drug transporters and their impact on drug pharmacokinetics and pharmacodynamics. The project will involve studying the classification and function of drug transporters, as well as their role in drug-drug interactions and drug resistance. Additionally, the project will explore the techniques used to study drug transporters and their implications in drug development and personalized medicine. By understanding the biochemistry of drug transporters, this project aims to contribute to the optimization of drug therapy and the development of more effective and safe drugs.
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