<p> </p><p>

Chapter ONE

</p><p>1.0 &nbsp; &nbsp; Introduction</p><p>1.1 &nbsp; &nbsp; Amino-butyric acid</p><p>1.1.1 Biochemistry and Pharmacokinetics</p><p>1.1.2 Mechanism of action</p><p>1.1.3 Deficiency States</p><p>

Chapter TWO

</p><p>2.0 &nbsp; &nbsp; The major inhibitory neurotransmitter in nervous system</p><p>2.1 &nbsp; &nbsp; Physiology and Pharmacology of GABAA ,GABAB, GABAC Receptors</p><p>2.1.1 Structure and function of GABAA Receptors</p><p>

Chapter THREE

</p><p>3.0 &nbsp; &nbsp; Metabolism of plants</p><p>3.1 &nbsp; &nbsp; Glutamate Decarboxylase</p><p>3.2 &nbsp; &nbsp; transaminase</p><p>3.3 &nbsp; &nbsp; Succinic semialdehyde dehydrogenase</p><p>3.4 &nbsp; &nbsp; γ- Hydroxybutyric acid</p><p>3.5 &nbsp; &nbsp; shunt and the metabolism of nitrogen</p><p>3.5.1 Impact of &nbsp; shunt on the nitrogen metabolism</p><p>3.5.2 Regulation of shunt by nitrogen availability</p><p>

Chapter FOUR

</p><p>4.0 &nbsp; &nbsp; Clinical application</p><p>4.1 &nbsp; &nbsp; Side effects and toxicity</p><p>

Chapter FIVE

</p><p>5.0 &nbsp; &nbsp; Conclusion</p><p>References</p> <br><p></p>