Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii | Blazingprojects Postgraduate Thesis
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Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Phytochemicals
  • 2.2Phytochemical Analysis Methods
  • 2.3Anti-inflammatory Activities in Plants
  • 2.4Previous Studies on Crateva Adansonii
  • 2.5Phytochemical Composition of Crateva Adansonii
  • 2.6Anti-inflammatory Potential of Crateva Adansonii
  • 2.7Comparison with Other Plant Extracts
  • 2.8Mechanisms of Action
  • 2.9Clinical Applications
  • 2.10Future Research Directions

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Selection of Research Approach
  • 3.3Data Collection Methods
  • 3.4Sampling Techniques
  • 3.5Data Analysis Procedures
  • 3.6Ethical Considerations
  • 3.7Validity and Reliability
  • 3.8Limitations of Methodology

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Phytochemical Analysis Results
  • 4.2Anti-inflammatory Activity Findings
  • 4.3Comparison with Control Groups
  • 4.4Statistical Analysis of Results
  • 4.5Interpretation of Findings
  • 4.6Discussion on Mechanisms of Action
  • 4.7Implications for Clinical Practice
  • 4.8Future Research Recommendations

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Recommendations for Further Research
  • 5.4Implications for the Field
  • 5.5Closing Remarks

Thesis Abstract

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 and Cyclooxygenase- 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research (Ryan & Majno, 1983). Attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti- inflammatory drugs.
Anti-inflammation was carried out using 12 rats which was divided into three groups of 4 rats each. Group 1 and 2 served as the negative and positive control respectively. Group 3 received 25mg/kg b.w. of the dichloromethane fraction of methanol extract of Crateva adansonii showed significance anti-inflammatory activity when compared with the standard difference used.

Thesis Overview

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