Exploring the use of stem cell therapy in treating osteoarthritis in dogs

Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting dogs, leading to pain, reduced mobility, and decreased quality of life. Traditional treatments for osteoarthritis provide symptomatic relief but do not address the underlying degenerative changes in the joint. Stem cell therapy has emerged as a promising approach to treat osteoarthritis by promoting tissue regeneration and reducing inflammation. This thesis explores the use of stem cell therapy in treating osteoarthritis in dogs, aiming to evaluate its effectiveness, safety, and potential benefits. Chapter 1 introduces the background of the study, highlighting the prevalence and impact of osteoarthritis in dogs. The problem statement emphasizes the limitations of current treatment options and the need for innovative therapies. The objectives of the study include assessing the efficacy of stem cell therapy in managing osteoarthritis symptoms and investigating its long-term effects. The scope of the study focuses on clinical trials and experimental research involving canine subjects. The significance of the study lies in its potential to advance veterinary medicine and improve the welfare of dogs suffering from osteoarthritis. Chapter 2 presents a comprehensive literature review on stem cell therapy for osteoarthritis, covering topics such as the mechanism of action of stem cells, different sources of stem cells, previous studies on stem cell therapy in dogs, and outcomes of clinical trials. The review synthesizes existing knowledge and identifies gaps in the current understanding of stem cell therapy for osteoarthritis in dogs. Chapter 3 details the research methodology, including the selection criteria for canine participants, stem cell isolation and characterization techniques, treatment protocols, outcome measures, and statistical analysis methods. The methodology aims to ensure the scientific rigor and reproducibility of the study findings. Chapter 4 discusses the findings of the study, including the efficacy of stem cell therapy in reducing pain, improving joint function, and enhancing tissue regeneration in dogs with osteoarthritis. The results are analyzed in the context of previous research and clinical implications for veterinary practice. Chapter 5 concludes the thesis by summarizing the key findings, discussing their implications for veterinary medicine, and offering recommendations for future research directions. The study contributes to the growing body of evidence supporting the use of stem cell therapy as a viable treatment option for osteoarthritis in dogs, with the potential to revolutionize the management of this debilitating condition.