Determination of heavy metal in effluents from some selected pharmaceutical companies | Blazingprojects Postgraduate Thesis
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Determination of heavy metal in effluents from some selected pharmaceutical companies

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Heavy Metals
  • 2.2Sources of Heavy Metals in Effluents
  • 2.3Health and Environmental Impacts of Heavy Metals
  • 2.4Regulations and Guidelines on Heavy Metal Discharge
  • 2.5Analytical Methods for Heavy Metal Detection
  • 2.6Previous Studies on Heavy Metal Contamination
  • 2.7Treatment Technologies for Heavy Metal Removal
  • 2.8Best Practices in Heavy Metal Management
  • 2.9Case Studies on Heavy Metal Pollution
  • 2.10Emerging Trends in Heavy Metal Research

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Techniques
  • 3.3Data Collection Methods
  • 3.4Data Analysis Procedures
  • 3.5Ethical Considerations
  • 3.6Research Limitations
  • 3.7Research Validity and Reliability
  • 3.8Research Instrumentation

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Analysis of Heavy Metal Concentrations
  • 4.3Comparison with Regulatory Standards
  • 4.4Identification of Contaminated Sites
  • 4.5Factors Influencing Heavy Metal Levels
  • 4.6Implications for Environmental Management
  • 4.7Recommendations for Policy and Practice
  • 4.8Suggestions for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions
  • 5.3Implications for Industry and Society
  • 5.4Recommendations for Action
  • 5.5Areas for Future Research

Thesis Abstract

The concentration of some heavy metals in the effluents of five (5) companies operating in Enugu State, Nigeria were determined using atomic absorption spectrophotometer. The heavy metals detected in this study include Arsenic (AS), Cadmium (Cd), Chromium (Cr), Iron (Fe), Mercury (Hg), Manganese (Mn), Nickel (Ni), Lead (Pb) and Zinc (Zn). Most of the samples were found to contain the metals in various concentrations. Most of concentration were above the W.H.O maximum recommended contaminant concentration level. The highest average concentration of heavy metal was detected in Lead with a concentration of 2.685mg/L. The highest average concentration were found to be 0.253mg/L for Arsenic, 0.105mg/L for Cadmium, 0.122mg/L for Chromium, 2.120mg/L for Iron, 0.050mg/L for mercury, 1.522Mg/L for Manganese, 0.546mg/L for Nickel and 0.885mg/L for Zinc. This study reveals the need for enforcing adequate effluent treatment method before their discharge to surface water or environment to reduce their potential environmental hazards.

Thesis Overview

<p> <strong>6.0 INTRODUCTION<br>6.1 Background of the Study</strong><br>Heavy metal is a member of a loosely defined sub-set of elements that exhibit metallic properties. This includes the transition metals metalloids, lanthanides and actinides (IUPAC).<br>Pharmaceutical effluents are waste generated by pharmaceutical industries during the process of drugs manufacturing. The increase in demand for pharmaceuticals has resulted in a consequent increase in pharmaceutical manufacturing companies in the country and hence increased pharmaceutical waste which most times contain substantial amount of heavy metals.<br>Heavy metals such as lead, mercury, cadmium Nickel, chromium and other toxic organic chemicals or phenolic compounds discharged from pharmaceutical industries are known to affect the surface and ground water (Foess and Ericson, 1980). These effluents are usually discharged into the environment and when improperly handled and disposed, they affect both human health and the environment (Osaigbovo and Orhue, 2006, Ayodele et al, 1996, Anetor et al., 1999).<br>Studies showed that for the last 40 years, various devastating ecological effects and human disasters have arisen majorly from industrial wastes containing heavy metals causing environmental degradation (Abdel-Shafy and Abdel-Basir, 1991 Sridhar et al 2000). Following the increasing use of pharmaceuticals products in recent years, this having caused the industry to become one of the major contributors to industrial waste containing heavy metal in the environment. It is on this background that the project is investigating to determine presence of heavy metals from pharmaceutical effluent<br><strong>1.2 statement of the problem</strong><br>Various devastating ecological effects and human disasters have arisen majorly from industrial wastes containing heavy metals causing environmental degradation (Abdel-Shafy and Abdel-Basir, 1991 Sridhar et al 2000).<br>Following the increasing use of pharmaceuticals products in recent years, this having caused the industry to become one of the major contributors to industrial waste containing heavy metal in the environment.<br><strong>1.3 OBJECTIVE OF THE STUDY</strong><br>The objective of this project is to determine the content and concentrations of heavy metals in effluents from some selected pharmaceutical companies in Enugu.<br><strong>1.4 Scope /Delimitation of the Study</strong><br>This project focused on the identification of heavy metals and their concentrations in effluent from some selected pharmaceutical companies in Enugu with a view to determining the rate of introduction of such metals into the environment.<br>It does not cover the treatment or purification of such effluent.<br><strong>1.4.1 Limitation</strong><br>The limitation of this project work include the challenges encountered in collecting effluent samples from pharmaceutical companies.<br>Financial constrain also pose some difficulties to the success of this project work.<br><strong>1.5 Method of Research</strong><br>The method of research adopted include the following:<br>v The use of World Wild Web (internet)<br>v Pharmaceutical handbook was used in writing the literature<br>v Samples were collected form pharmaceutical companies at their point of discharge.<br>v The collected samples were analyzed in the laboratory by the use of Atomic Absorption spectrophotometer (AAS) to identify the metals and obtain their concentrations in every sample. <br></p>

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