Thesis Abstract

Abstract
Enamel lesions resulting from demineralization pose a significant concern in dental health. The use of nano-hydroxyapatite has emerged as a promising approach for remineralization therapy. This thesis presents the findings from a randomized clinical trial that aimed to assess the efficacy of nano-hydroxyapatite in remineralizing enamel lesions. The study involved a sample of participants with varying degrees of enamel lesions, who were randomly assigned to either a treatment group receiving nano-hydroxyapatite or a control group receiving a placebo. Over a specified period, various clinical parameters and imaging techniques were used to evaluate the extent of remineralization in the enamel lesions. The introduction chapter sets the stage for the study, providing a background to enamel lesions, the problem statement, research objectives, limitations, scope, significance, and defining key terms. The literature review chapter critically examines existing studies on nano-hydroxyapatite and remineralization techniques, providing a comprehensive understanding of the theoretical framework underlying the study. In the research methodology chapter, the study design, participant selection criteria, intervention protocols, outcome measures, data collection methods, and statistical analysis plan are elaborated upon. The discussion of findings chapter presents a detailed analysis of the results obtained from the clinical trial, discussing the efficacy of nano-hydroxyapatite in promoting remineralization and comparing outcomes between the treatment and control groups. The conclusion and summary chapter highlight the key findings of the study, discussing the implications for dental practice and potential areas for future research. Overall, the results suggest that nano-hydroxyapatite shows promise as an effective agent for remineralizing enamel lesions, with significant improvements observed in the treatment group compared to the control group. This study contributes valuable insights to the field of dental research, emphasizing the potential of nano-hydroxyapatite in enhancing enamel remineralization and supporting the development of novel therapeutic strategies for managing enamel lesions.

Thesis Overview

The project titled "Assessment of the Efficacy of Nano-hydroxyapatite in Remineralization of Enamel Lesions: A Randomized Clinical Trial" seeks to investigate the effectiveness of nano-hydroxyapatite in the remineralization of enamel lesions through a randomized clinical trial. Enamel lesions, commonly caused by factors such as poor oral hygiene, acidic diets, and bacterial activity, can lead to tooth decay and other dental issues if left untreated. Remineralization is a vital process that helps restore minerals to enamel and reverse the early stages of tooth decay. Nano-hydroxyapatite, a synthetic form of the mineral naturally found in teeth and bones, has shown promise in promoting enamel remineralization due to its similarities to natural enamel composition. This research aims to provide empirical evidence on the efficacy of nano-hydroxyapatite in enhancing the remineralization process and potentially improving overall dental health outcomes. By conducting a randomized clinical trial, the study will compare the effectiveness of nano-hydroxyapatite treatment against conventional methods or a control group. Various parameters such as enamel hardness, mineral content, surface morphology, and patient-reported outcomes will be assessed to evaluate the impact of nano-hydroxyapatite on enamel remineralization. The findings of this research project have the potential to contribute significantly to the field of dentistry by providing valuable insights into the use of nano-hydroxyapatite as a novel approach to managing enamel lesions and promoting dental health. Ultimately, the goal of this study is to advance our understanding of remineralization techniques and potentially offer a more effective and patient-friendly treatment option for enamel lesions.