The response of lipid profile to the administration of mezoneuron benthamianum baill (jenifiran) ethanolic extract in adult wistar rats | Blazingprojects Postgraduate Thesis
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The response of lipid profile to the administration of mezoneuron benthamianum baill (jenifiran) ethanolic extract in adult wistar rats

 

Table Of Contents


  • ContentsTitle page                                                                                        Certification                                                                                              Dedication                                                                                     Acknowledgements                                                                                Table of contents                                                                        List of Figures                                                                                List of Table                                                                                           Abstract                                                                                            CHAPTER ONE1.0     Introduction1.1     Medicinal Plants1.2     Aim of StudyCHAPTER TWO2.0     Literature review2.1     Medicinal Plants and their uses2.
  • 1.1Mezoneuron benthamianum baill                                      
  • 2.2    Lipid Profile2.
  • 2.1Effect of medicinal plants on Lipid profileCHAPTER THREE3.0     Materials and Methods3.1     Apparatus and Equipments3.2     Chemical Reagents3.3     Collection and extraction of plant materials3.
  • 3.1Mezoneuron benthamianum baill3.4       Practical history and animal management3.5       Drug administration3.6       Sacrificing of Rats3.7       Biochemical Analysis3.
  • 7.1    Triglycerides3.7.
  • 1.1Principle3.7.
  • 1.2Reagent composition3.7.
  • 1.3Preparation of reagents3.7.
  • 1.4Procedure3.
  • 7.2HDL- Cholesterol3.7.
  • 2.1Principle3.7.
  • 2.2Preparation of reagents3.7.
  • 2.3Procedure3.8     Statistical AnalysisCHAPTER FOUR4.0     ResultsCHAPTER FIVE5.0     Discussion, Conclusion and Recommendation5.1     Discussion5.2     Conclusion5.3     RecommendationReferencesLIST OF FIGURESFigure 1 –Mezoneuron benthamianum baill                                            Figure 2 – Bar chart showing the level of cholesterol in adult wistar ratsFigure 3 – Bar chart showing the level of HDL in adult wistar ratsFigure 4 – Bar chart showing the level of LDL in adult wistar ratsFigure 5 – Bar chart showing the level of triglycerides in adult wistar ratsLIST OF TABLETable 1 – Groups and treatment administeredTable 2- Procedure triglyceride determinationTable 3 – Procedure for HDL determinationTable 4- Cholesterol CHOD-PAP assayTable 5- Showing the level of cholesterol, HDL, LDL andtriglycerides in adult wistar rats.

Thesis Abstract

This research work was carried out to determine the effect of Menzoneuron benthamainum on fasting blood sugar level of adult wistar rats. Twenty wistar rats (both male and female) weighing between 140g to 160g were used for this research project. They were acclimatized for 14 days after which the animals were grouped into four groups of five rats each. Each animal were administered based on their body weight. The dose given to animals in group A was 300mg/kg body weight of Menzoneuron benthamainum, Group B was given 500mg/kg body weight of Menzoneuron benthamainum, Group C was given 700mg/kg body weight of Menzoneuron benthamainum and group D (control group) was given distilled water. The administration lasted for thirteen days. Blood samples were collected from the tail of the animals and the Lipid profile level for each of the animals was tested.

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