The response of lipid profile to the administration of mezoneuron benthamianum baill (jenifiran) ethanolic extract in adult wistar rats | Blazingprojects Postgraduate Thesis
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The response of lipid profile to the administration of mezoneuron benthamianum baill (jenifiran) ethanolic extract in adult wistar rats

 

Table Of Contents

Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Lipid Profile
  • 2.2Importance of Lipid Profile in Health
  • 2.3Factors Affecting Lipid Profile
  • 2.4Lipid Profile Testing Methods
  • 2.5Normal Lipid Profile Levels
  • 2.6Abnormal Lipid Profile Implications
  • 2.7Role of Diet in Lipid Profile Management
  • 2.8Exercise and Lipid Profile
  • 2.9Medications and Lipid Profile
  • 2.10Research Studies on Lipid Profile

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Methods
  • 3.3Data Collection Techniques
  • 3.4Data Analysis Procedures
  • 3.5Ethical Considerations
  • 3.6Research Limitations
  • 3.7Reliability and Validity
  • 3.8Research Instrumentation

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Data Presentation and Analysis
  • 4.2Lipid Profile Responses to Extract Administration
  • 4.3Comparison of Pre and Post-Administration Results
  • 4.4Correlation Analysis
  • 4.5Discussion on Findings
  • 4.6Implications of the Results
  • 4.7Recommendations for Further Research
  • 4.8Practical Applications of the Study

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Implications for Practice
  • 5.4Recommendations
  • 5.5Contribution to Knowledge

Thesis Abstract

This research work was carried out to determine the effect of Menzoneuron benthamainum on fasting blood sugar level of adult wistar rats. Twenty wistar rats (both male and female) weighing between 140g to 160g were used for this research project. They were acclimatized for 14 days after which the animals were grouped into four groups of five rats each. Each animal were administered based on their body weight. The dose given to animals in group A was 300mg/kg body weight of Menzoneuron benthamainum, Group B was given 500mg/kg body weight of Menzoneuron benthamainum, Group C was given 700mg/kg body weight of Menzoneuron benthamainum and group D (control group) was given distilled water. The administration lasted for thirteen days. Blood samples were collected from the tail of the animals and the Lipid profile level for each of the animals was tested.

Thesis Overview

<p> </p><p><em>Contents</em></p><p><em>Title page &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p><em>Certification &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p><em>Dedication &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; </em></p><p><em>Acknowledgements &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p><em>Table of contents &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p><em>List of Figures &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p><em>List of Table &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; </em></p><p><em>Abstract &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p>CHAPTER ONE</p><p>1.0 &nbsp; &nbsp; Introduction</p><p>1.1 &nbsp; &nbsp; Medicinal Plants</p><p>1.2 &nbsp; &nbsp; Aim of Study</p><p>CHAPTER TWO</p><p>2.0 &nbsp; &nbsp; Literature review</p><p>2.1 &nbsp; &nbsp; Medicinal Plants and their uses</p><p>2.1.1 <em>Mezoneuron benthamianum baill &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p>2.2 &nbsp; &nbsp; Lipid Profile</p><p>2.2.1 Effect of medicinal plants on Lipid profile</p><p>CHAPTER THREE</p><p>3.0 &nbsp; &nbsp; Materials and Methods</p><p>3.1 &nbsp; &nbsp; Apparatus and Equipments</p><p>3.2 &nbsp; &nbsp; Chemical Reagents</p><p>3.3 &nbsp; &nbsp; Collection and extraction of plant materials</p><p>3.3.1 Mezoneuron benthamianum baill</p><p>3.4 &nbsp; &nbsp; &nbsp; Practical history and animal management</p><p>3.5 &nbsp; &nbsp; &nbsp; Drug administration</p><p>3.6 &nbsp; &nbsp; &nbsp; Sacrificing of Rats</p><p>3.7 &nbsp; &nbsp; &nbsp; Biochemical Analysis</p><p>3.7.1 &nbsp; &nbsp; Triglycerides</p><p>3.7.1.1 Principle</p><p>3.7.1.2 Reagent composition</p><p>3.7.1.3 Preparation of reagents</p><p>3.7.1.4 Procedure</p><p>3.7.2 HDL- Cholesterol</p><p>3.7.2.1 Principle</p><p>3.7.2.2 Preparation of reagents</p><p>3.7.2.3 Procedure</p><p>3.8 &nbsp; &nbsp; Statistical Analysis</p><p>CHAPTER FOUR</p><p>4.0 &nbsp; &nbsp; Results</p><p>CHAPTER FIVE</p><p>5.0 &nbsp; &nbsp; Discussion, Conclusion and Recommendation</p><p>5.1 &nbsp; &nbsp; Discussion</p><p>5.2 &nbsp; &nbsp; Conclusion</p><p>5.3 &nbsp; &nbsp; Recommendation</p><p>References</p><p>LIST OF FIGURES</p><p>Figure 1 –<em>Mezoneuron benthamianum baill &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></p><p>Figure 2 – Bar chart showing the level of cholesterol in adult wistar rats</p><p>Figure 3 – Bar chart showing the level of HDL in adult wistar rats</p><p>Figure 4 – Bar chart showing the level of LDL in adult wistar rats</p><p>Figure 5 – Bar chart showing the level of triglycerides in adult wistar rats</p><p>LIST OF TABLE</p><p>Table 1 – Groups and treatment administered</p><p>Table 2- Procedure triglyceride determination</p><p>Table 3 – Procedure for HDL determination</p><p>Table 4- Cholesterol CHOD-PAP assay</p><p>Table 5- Showing the level of cholesterol, HDL, LDL and</p><p>triglycerides in adult wistar rats.</p> <br><p></p>
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