Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats
Table Of Contents
Chapter ONE
INTRODUCTION
- 1.1Introduction
- 1.2Background of Study
- 1.3Problem Statement
- 1.4Objective of Study
- 1.5Limitation of Study
- 1.6Scope of Study
- 1.7Significance of Study
- 1.8Structure of the Research
- 1.9Definition of Terms
Chapter TWO
LITERATURE REVIEW
- 2.1Overview of Liver Functions
- 2.2Allium Ascalonicum: Botanical Description
- 2.3Traditional Uses of Allium Ascalonicum
- 2.4Chemical Composition of Allium Ascalonicum
- 2.5Pharmacological Properties of Allium Ascalonicum
- 2.6Previous Studies on Allium Ascalonicum Extracts
- 2.7Liver Function Tests: ASP, ALT, AST, Bilirubin
- 2.8Effects of Herbal Extracts on Liver Functions
- 2.9Mechanisms of Action of Herbal Extracts on the Liver
- 2.10Current Trends in Herbal Medicine Research
Chapter THREE
RESEARCH METHODOLOGY
- 3.1Research Design and Methodology
- 3.2Selection of Experimental Animals
- 3.3Administration of Allium Ascalonicum Extract
- 3.4Sample Collection and Analysis
- 3.5Liver Function Test Procedures
- 3.6Data Analysis Techniques
- 3.7Ethical Considerations in Animal Research
- 3.8Statistical Analysis Methods
Chapter FOUR
DATA PRESENTATION AND ANALYSIS
- 4.1Demographic Characteristics of Experimental Animals
- 4.2Baseline Liver Function Test Results
- 4.3Effects of Allium Ascalonicum Extract on ASP Levels
- 4.4Effects of Allium Ascalonicum Extract on ALT Levels
- 4.5Effects of Allium Ascalonicum Extract on AST Levels
- 4.6Effects of Allium Ascalonicum Extract on Bilirubin Levels
- 4.7Comparison with Control Group Results
- 4.8Discussion on the Findings
Chapter FIVE
SUMMARY, CONCLUSION AND RECOMMENDATIONS
- 5.1Summary of Research Findings
- 5.2Conclusions Drawn from the Study
- 5.3Implications of the Research
- 5.4Recommendations for Future Studies
- 5.5Contribution to the Field of Herbal Medicine Research
Thesis Abstract
The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).
Thesis Overview
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