Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats | Blazingprojects Postgraduate Thesis
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Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Liver Functions
  • 2.2Allium Ascalonicum Ethanol Extract
  • 2.3Liver Function Tests
  • 2.4Previous Studies on Allium Ascalonicum
  • 2.5Effects of Ethanol Extracts on Liver Functions
  • 2.6Mechanisms of Action of Allium Ascalonicum
  • 2.7Pharmacological Properties of Allium Ascalonicum
  • 2.8Toxicity and Safety Profile of Allium Ascalonicum
  • 2.9Interaction of Allium Ascalonicum with Liver Enzymes
  • 2.10Conclusion of Literature Review

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Technique
  • 3.3Data Collection Methods
  • 3.4Variables and Measures
  • 3.5Data Analysis Plan
  • 3.6Ethical Considerations
  • 3.7Research Limitations
  • 3.8Research Validity and Reliability

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Descriptive Analysis of Data
  • 4.2Effect of Allium Ascalonicum Ethanolic Extract on Liver Functions
  • 4.3Comparison of Liver Enzyme Levels Before and After Treatment
  • 4.4Statistical Analysis of Results
  • 4.5Interpretation of Findings
  • 4.6Discussion of Results in Relation to Previous Studies
  • 4.7Implications of the Findings
  • 4.8Suggestions for Further Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Recommendations
  • 5.4Contribution to Knowledge
  • 5.5Implications for Practice

Thesis Abstract

The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).

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