Phytochemical analysis and the anti-inflammatory activities of methanol extract of crateva adansonii | Blazingprojects Postgraduate Thesis
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Phytochemical analysis and the anti-inflammatory activities of methanol extract of crateva adansonii

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of study
  • 1.3Problem Statement
  • 1.4Objective of study
  • 1.5Limitation of study
  • 1.6Scope of study
  • 1.7Significance of study
  • 1.8Structure of the research
  • 1.9Definition of terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Phytochemicals
  • 2.2Phytochemicals in Crateva adansonii
  • 2.3Anti-inflammatory Properties of Plants
  • 2.4Previous Studies on Crateva adansonii
  • 2.5Mechanisms of Anti-inflammatory Activity
  • 2.6Methods of Extracting Phytochemicals
  • 2.7Importance of Studying Phytochemicals
  • 2.8Role of Methanol Extracts in Research
  • 2.9Comparison with Other Plant Extracts
  • 2.10Future Research Directions

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Method
  • 3.3Data Collection Techniques
  • 3.4Data Analysis Procedures
  • 3.5Ethical Considerations
  • 3.6Instrumentation Used
  • 3.7Statistical Tools Applied
  • 3.8Validation of Research Methods

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Phytochemical Analysis Results
  • 4.2Anti-inflammatory Activity Findings
  • 4.3Comparison with Control Groups
  • 4.4Interpretation of Data
  • 4.5Discussion on Phytochemical Components
  • 4.6Correlation between Phytochemicals and Activity
  • 4.7Implications of Findings
  • 4.8Recommendations for Further Studies

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Contributions to the Field
  • 5.4Implications for Practice
  • 5.5Limitations of the Study
  • 5.6Suggestions for Future Research
  • 5.7Practical Applications
  • 5.8Final Thoughts and Recommendations

Thesis Abstract

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research, attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti-inflammatory drugs.
Anti-inflammation was carried out using 11 rats. That was divided into three groups of four rats each. Group 1 and 2 served as the positive and negative control respectively. Groups 3 and 4 received 200mg/kg b.w and 600mg/kg b.w. of the extracts respectively. However, it was discovered that the stem bark of crateva Adansonii showed greater significance anti-inflammatory activity when compared with the standard.

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