Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii | Blazingprojects Postgraduate Thesis
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Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Introduction to Literature Review
  • 2.2Overview of Phytochemical Analysis
  • 2.3Anti-Inflammatory Activities of Phytochemicals
  • 2.4Previous Studies on Crateva Adansonii
  • 2.5Dichloromethane Fraction Extraction Methods
  • 2.6Methanol Extract Preparation
  • 2.7Phytochemical Analysis Techniques
  • 2.8Anti-Inflammatory Assays
  • 2.9Mechanisms of Anti-Inflammatory Actions
  • 2.10Summary of Literature Review

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Introduction to Research Methodology
  • 3.2Research Design
  • 3.3Sampling Techniques
  • 3.4Data Collection Methods
  • 3.5Data Analysis Procedures
  • 3.6Experimental Setup
  • 3.7Statistical Analysis
  • 3.8Ethical Considerations

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Introduction to Discussion of Findings
  • 4.2Phytochemical Analysis Results
  • 4.3Anti-Inflammatory Activities Findings
  • 4.4Comparison with Previous Studies
  • 4.5Interpretation of Results
  • 4.6Implications of Findings
  • 4.7Recommendations for Further Research
  • 4.8Conclusion of Findings Discussion

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary of the Project Research

Thesis Abstract

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 and Cyclooxygenase- 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research (Ryan & Majno, 1983). Attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti- inflammatory drugs.
Anti-inflammation was carried out using 12 rats which was divided into three groups of 4 rats each. Group 1 and 2 served as the negative and positive control respectively. Group 3 received 25mg/kg b.w. of the dichloromethane fraction of methanol extract of Crateva adansonii showed significance anti-inflammatory activity when compared with the standard difference used.

Thesis Overview

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