INTRODUCTION
LITERATURE REVIEW
RESEARCH METHODOLOGY
DATA PRESENTATION AND ANALYSIS
SUMMARY, CONCLUSION AND RECOMMENDATIONS
Jatropha tanjorensis has been consumed as a leafy vegetable and as a medicinal plant in Nigeria has shown hematological, antimalarial, antimicrobial, hypoglyceamic, hypolipidemic and antihypertensive activities. This study was designed to investigate the effect of ethanol root extract of jatropha tanjorensis on the kidney function of albino Wistar rat. Twenty rats (20) adult female adults, the animals were divided into five groups. Group I served as control and was administered water and normal rat feed, group 2 was administered 100mg/kgbwt of extract, group 3 was administered 250mg/kgbwt of extract and finally group 4 was administered 500mg/kgbwt of extract. The administration lasted for 14 days and the experimental animals were sacrificed and blood samples collected. The urea, creatinine, total bilirubin and direct bilirubin level were assayed for and it was observed that the group II,III and IV showed significant decrease in urea, total bilirubin and direct bilirubin concentrations group II,III and IV also showed siginificant increase in creatinine level. From the results, it has been established that jatropha tanjorensis possess kidney protective properties.
Keywords Creatinine, Direct bilirubin, Jatropha Tanjorensis, Total bilirubin and Urea
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