Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats | Blazingprojects Postgraduate Thesis
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Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Introduction to Literature Review
  • 2.2Overview of Antioxidants
  • 2.3Superoxide Dismutase (SOD) in Health
  • 2.4Catalase Function and Importance
  • 2.5Malondialdehyde (MDA) as a Biomarker
  • 2.6Telferia Occidentalis in Traditional Medicine
  • 2.7Vernonia Amygdalina and Its Health Benefits
  • 2.8Previous Studies on Antioxidants and High Sucrose Diet
  • 2.9Effects of High Sucrose Diet on Brain, Plasma, and Liver
  • 2.10Summary of Literature Review

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Introduction to Research Methodology
  • 3.2Research Design and Approach
  • 3.3Selection of Animal Model
  • 3.4Experimental Procedures
  • 3.5Data Collection Methods
  • 3.6Data Analysis Techniques
  • 3.7Ethical Considerations
  • 3.8Limitations of the Methodology
  • 3.9Validation of Results

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Introduction to Discussion of Findings
  • 4.2Effects of Telferia Occidentalis on SOD Levels
  • 4.3Impact of Vernonia Amygdalina on Catalase Activity
  • 4.4MDA Levels in Brain, Plasma, and Liver
  • 4.5Comparison of Antioxidant Effects in Different Organs
  • 4.6Interactions between High Sucrose Diet and Antioxidants
  • 4.7Implications of Findings on Health
  • 4.8Future Research Directions

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary of Project Research

Thesis Abstract

This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others were fed with normal rat chow. Antioxidant status were analysed in the brain, plasma and heart after four weeks of feeding. The result shows the imbalance caused by high sucrose diets having an effect on the antioxidants as the levels of superoxide dismutase, malondialdehyde and catalase in the liver, brain and plasma were significantly reduced (p<0.05). Therefore, moderate consumption of vegetable extracts can modulate antioxidant activity.

Thesis Overview

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