Cardio protective activities of n-hexane extract of desmodium velutinum stem on albino wister rat | Blazingprojects Postgraduate Thesis
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Cardio protective activities of n-hexane extract of desmodium velutinum stem on albino wister rat

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Cardiovascular Diseases
  • 2.2Desmodium Velutinum as a Medicinal Plant
  • 2.3Previous Studies on Cardio Protective Activities
  • 2.4Mechanisms of Action on Cardiovascular System
  • 2.5Chemical Constituents of Desmodium Velutinum
  • 2.6Pharmacological Properties of Desmodium Velutinum
  • 2.7Animal Models Used in Cardio Protective Studies
  • 2.8Comparative Studies with Other Plant Extracts
  • 2.9Clinical Trials and Human Studies
  • 2.10Gaps in Existing Literature

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Selection of Research Methods
  • 3.3Data Collection Procedures
  • 3.4Sampling Techniques
  • 3.5Data Analysis Methods
  • 3.6Ethical Considerations
  • 3.7Validity and Reliability
  • 3.8Research Limitations

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Presentation of Data
  • 4.2Analysis of Findings
  • 4.3Comparison with Hypotheses
  • 4.4Interpretation of Results
  • 4.5Discussion of Results in Relation to Literature
  • 4.6Implications of Findings
  • 4.7Recommendations for Future Research
  • 4.8Practical Applications

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Contributions to Knowledge
  • 5.4Practical Implications
  • 5.5Recommendations for Practice
  • 5.6Recommendations for Policy
  • 5.7Recommendations for Further Research
  • 5.8Conclusion Statement

Thesis Abstract

This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing 3.6g of the cow’s brain twice a day for seven days. Rats on group two was fed with only grower’s mash and water for seven days; rats in group three was later administered orally 2ml of dissolved vasoprin drug once in a day for 3 days. Rats in group four were also administered orally 0.5ml of the liquid drug extract of Desmodium Velutinum stem once a day for 3 days. During these three (3) days, the rats were given grower’s mash and water. After the feeding period, the rate fed with the cow’s brain showed a significant increases in the activities of marker enzymes such as creatine kinase (CK), creatine kinase MB (CKMB), Aspartatatranseaminase (AST), Alaninetransminase (ALT), and lactatedehydrogenase. This study shows that N-hexane extract of Desmodium Velutinum stem posses cardio protective effect on albino wister rats than the known drug (vasoprin) if only one can increase the dosage of the extract for a period of time.

Thesis Overview

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