Cardio protective activities of n-hexane extract of desmodium velutinum stem on albino wister rat
Table Of Contents
Chapter ONE
INTRODUCTION
- 1.1Introduction
- 1.2Background of Study
- 1.3Problem Statement
- 1.4Objective of Study
- 1.5Limitation of Study
- 1.6Scope of Study
- 1.7Significance of Study
- 1.8Structure of the Research
- 1.9Definition of Terms
Chapter TWO
LITERATURE REVIEW
- 2.1Overview of Cardiovascular Diseases
- 2.2Desmodium Velutinum and Its Medicinal Properties
- 2.3Previous Studies on Cardio Protective Activities
- 2.4Mechanisms of Action of N-Hexane Extracts
- 2.5Animal Models Used in Cardio Protective Studies
- 2.6Pharmacological Effects of Desmodium Velutinum Stem Extract
- 2.7Comparison with Other Natural Extracts
- 2.8Clinical Trials and Human Studies
- 2.9Safety and Toxicity Profile
- 2.10Gaps in Existing Literature
Chapter THREE
RESEARCH METHODOLOGY
- 3.1Research Design and Rationale
- 3.2Selection of Study Participants
- 3.3Variables and Measures
- 3.4Data Collection Methods
- 3.5Data Analysis Techniques
- 3.6Ethical Considerations
- 3.7Pilot Study Details
- 3.8Limitations of the Research Methodology
Chapter FOUR
DATA PRESENTATION AND ANALYSIS
- 4.1Overview of Research Findings
- 4.2Cardio Protective Effects of N-Hexane Extract
- 4.3Impact on Biomarkers of Cardiovascular Health
- 4.4Comparison with Control Groups
- 4.5Dose-Response Relationship
- 4.6Adverse Effects and Safety Profile
- 4.7Discussion on Mechanisms of Action
- 4.8Implications for Clinical Practice
Chapter FIVE
SUMMARY, CONCLUSION AND RECOMMENDATIONS
- 5.1Summary of Findings
- 5.2Conclusions Drawn from the Study
- 5.3Recommendations for Future Research
- 5.4Practical Applications and Implications
- 5.5Final Thoughts and Closing Remarks
Thesis Abstract
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing 3.6g of the cow’s brain twice a day for seven days. Rats on group two was fed with only grower’s mash and water for seven days; rats in group three was later administered orally 2ml of dissolved vasoprin drug once in a day for 3 days.
Rats in group four were also administered orally 0.5ml of the liquid drug extract of Desmodium Velutinum stem once a day for 3 days. During these three (3) days, the rats were given grower’s mash and water. After the feeding period, the rate fed with the cow’s brain showed a significant increases in the activities of marker enzymes such as creatine kinase (CK), creatine kinase MB (CKMB), Aspartatatranseaminase (AST), Alaninetransminase (ALT), and lactatedehydrogenase. This study shows that N-hexane extract of Desmodium Velutinum stem posses cardio protective effect on albino wister rats than the known drug (vasoprin) if only one can increase the dosage of the extract for a period of time.
Thesis Overview
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