The effect of water extract of cola nitida pod on lipoprotein concentrations of albino wistar rats
Table Of Contents
Chapter ONE
INTRODUCTION
- 1.1Introduction
- 1.2Background of Study
- 1.3Problem Statement
- 1.4Objective of Study
- 1.5Limitation of Study
- 1.6Scope of Study
- 1.7Significance of Study
- 1.8Structure of the Research
- 1.9Definition of Terms
Chapter TWO
LITERATURE REVIEW
- 2.1Overview of Lipoproteins
- 2.2Cola Nitida Pod and its Components
- 2.3Lipoprotein Metabolism
- 2.4Effects of Herbal Extracts on Lipoprotein Concentrations
- 2.5Previous Studies on Cola Nitida Pod
- 2.6Lipid Profile and Cardiovascular Health
- 2.7Mechanisms of Lipoprotein Modification
- 2.8Role of Diet in Lipoprotein Regulation
- 2.9Lipoprotein Disorders and Diseases
- 2.10Summary of Literature Review
Chapter THREE
RESEARCH METHODOLOGY
- 3.1Research Design and Methodology
- 3.2Selection of Sample Population
- 3.3Preparation of Cola Nitida Pod Extract
- 3.4Animal Model and Experimental Setup
- 3.5Administration of Extract and Monitoring
- 3.6Data Collection and Analysis
- 3.7Statistical Methods Employed
- 3.8Ethical Considerations in Animal Studies
Chapter FOUR
DATA PRESENTATION AND ANALYSIS
- 4.1Lipoprotein Concentrations in Control Group
- 4.2Lipoprotein Changes in Experimental Group
- 4.3Comparative Analysis of Lipid Profiles
- 4.4Effects of Cola Nitida Pod Extract on Lipoproteins
- 4.5Discussion on Lipoprotein Modifications
- 4.6Interpretation of Experimental Results
- 4.7Comparison with Previous Studies
- 4.8Implications for Cardiovascular Health
Chapter FIVE
SUMMARY, CONCLUSION AND RECOMMENDATIONS
- 5.1Conclusion and Summary
- 5.2Summary of Findings
- 5.3Contributions to Existing Knowledge
- 5.4Recommendations for Future Research
- 5.5Final Remarks and Closing Thoughts
Thesis Abstract
Cola nitida has been in use in the eastern parts of Nigeria for the
management of certain ailments and as an aphrodisiac in the
management of some sexual dysfunctions. However the effects of this
extract in some health parameters in human objects have not been
reported. This work, then, was aimed at investigating the effect of
water extracts of kola pods on lipoprotein concentrations on albino
wistar rats.
Rats were used in this study and they were divided into several groups
and fed with a high calorie food (cow’s brain) so as to increase the
blood lipoprotein concentration in the rat models. The effect of the
water extracts of the sample used was compared with a known drug
and the results statistically compared to ascertain the effect of the
water extract on the rat models.
The results of this work indicate that water extracts of cola nitida pods
can be used in the management of mild lipoprotein dysfunctions thus
substantiating the reasons for its use in sexual erectile functions.
Thesis Overview
<p> 1.1 INTRODUCTION<br>Cola Nitida has been used in folk medicine as an aphrodisiac,<br>an appetite suppressant, to treat morning sickness, migraine headache,<br>and indigestion (Esimone et al., 2007). It has also been applied<br>directly to the skin to treat wounds and inflammation (Newall et al.,<br>1996)on the teeth and gums. There has also been speculations as to its<br>use in the treatment of peptic ulcer, however, in Nigeria there is no<br>record of the incidence of peptic ulcer.<br>According to Esimone (2007), cola nitida tree is native to West<br>Africa. Cola nuts are obtained from cola trees. Cola nitida belongs to<br>the genus cola and family steriliaceae. They are commonly used to<br>counteract hunger and thirst; in some cases it is used to control<br>vomiting in pregnant woman and also as a principal stimulant to keep<br>awake and withstand fatigue by students, drivers, and other menial<br>workers.<br>Lipoproteins are found in the liver and cells. The liver is the<br>largest organ inside the body. The liver is dark reddish-brown and<br>consists of two main lobes. There are over 300 billion specialized<br>cells in the liver that are connected by a well organized system of<br>“bile” ducts and blood vessels called the biliary system. <br></p>Blazingprojects Mobile App
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