THE EFFECT OF WATER EXTRACT OF COLA NITIDA POD ON LIPOPROTEIN CONCENTRATIONS OF ALBINO WISTAR RATS | Blazingprojects Postgraduate Thesis
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THE EFFECT OF WATER EXTRACT OF COLA NITIDA POD ON LIPOPROTEIN CONCENTRATIONS OF ALBINO WISTAR RATS

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Lipoproteins
  • 2.2Functions of Lipoproteins
  • 2.3Types of Lipoproteins
  • 2.4Role of Lipoproteins in Health and Disease
  • 2.5Cola Nitida Pod and its Extracts
  • 2.6Previous Studies on Cola Nitida Pod Extracts
  • 2.7Effects of Cola Nitida Pod Extracts on Health
  • 2.8Lipoprotein Concentrations in Research
  • 2.9Relationship Between Cola Nitida Pod Extracts and Lipoprotein Concentrations
  • 2.10Gaps in Literature on Lipoproteins and Cola Nitida Pod Extracts

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Method
  • 3.3Data Collection Techniques
  • 3.4Data Analysis Methods
  • 3.5Ethical Considerations
  • 3.6Validity and Reliability
  • 3.7Research Limitations
  • 3.8Timeframe for Research

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Findings
  • 4.2Lipoprotein Concentrations in Rats
  • 4.3Effects of Water Extract of Cola Nitida Pod
  • 4.4Comparison with Control Group
  • 4.5Statistical Analysis
  • 4.6Discussion on Results
  • 4.7Implications of Findings
  • 4.8Recommendations for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Contributions to Knowledge
  • 5.4Practical Applications
  • 5.5Recommendations
  • 5.6Areas for Further Research
  • 5.7Conclusion Statement

Thesis Abstract

Cola nitida has been in use in the eastern parts of Nigeria for the management of certain ailments and as an aphrodisiac in the management of some sexual dysfunctions. However the effects of this extract in some health parameters in human objects have not been reported. This work, then, was aimed at investigating the effect of water extracts of kola pods on lipoprotein concentrations on albino wistar rats. Rats were used in this study and they were divided into several groups and fed with a high calorie food (cow’s brain) so as to increase the blood lipoprotein concentration in the rat models. The effect of the water extracts of the sample used was compared with a known drug and the results statistically compared to ascertain the effect of the water extract on the rat models. The results of this work indicate that water extracts of cola nitida pods can be used in the management of mild lipoprotein dysfunctions thus substantiating the reasons for its use in sexual erectile functions.



Thesis Overview

<p> </p><div><p>Cola Nitida has been used in folk medicine as an aphrodisiac, an appetite suppressant, to treat morning sickness, migraine headache, and indigestion (Esimone et al., 2007). It has also been applied directly to the skin to treat wounds and inflammation (Newall et al., 1996)on the teeth and gums. There has also been speculations as to its use in the treatment of peptic ulcer, however, in Nigeria there is no record of the incidence of peptic ulcer. According to Esimone (2007), cola nitida tree is native to West Africa. Cola nuts are obtained from cola trees. Cola nitida belongs to the genus cola and family steriliaceae. They are commonly used to counteract hunger and thirst; in some cases it is used to control vomiting in pregnant woman and also as a principal stimulant to keep awake and withstand fatigue by students, drivers, and other menial workers. Lipoproteins are found in the liver and cells. The liver is the largest organ inside the body. The liver is dark reddish-brown and consists of two main lobes. There are over 300 billion specialized cells in the liver that are connected by a well organized system of “bile” ducts and blood vessels called the biliary system.</p></div><p></p><br> <br><p></p>

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