The effect of ethanolic extract of acanthus montanus on fasting blood sugar levels of adult wistar rats.. | Blazingprojects Postgraduate Thesis
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The effect of ethanolic extract of acanthus montanus on fasting blood sugar levels of adult wistar rats..

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of study
  • 1.3Problem Statement
  • 1.4Objective of study
  • 1.5Limitation of study
  • 1.6Scope of study
  • 1.7Significance of study
  • 1.8Structure of the research
  • 1.9Definition of terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Fasting Blood Sugar Levels
  • 2.2Diabetes Mellitus: Types and Symptoms
  • 2.3Acanthus montanus: Description and Traditional Uses
  • 2.4Phytochemical Constituents of Acanthus montanus
  • 2.5Previous Studies on Acanthus montanus and Blood Sugar Levels
  • 2.6Mechanisms of Action of Acanthus montanus on Blood Sugar
  • 2.7Animal Models in Blood Sugar Level Research
  • 2.8Effects of Ethanolic Extracts on Biological Systems
  • 2.9Methods of Extracting Bioactive Compounds
  • 2.10Regulation of Blood Sugar Levels in Rats

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design and Rationale
  • 3.2Sampling and Sample Size Determination
  • 3.3Data Collection Methods
  • 3.4Experimental Procedure
  • 3.5Data Analysis Techniques
  • 3.6Ethical Considerations
  • 3.7Validity and Reliability of Data
  • 3.8Statistical Tools and Software Used

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Effects of Acanthus montanus Extract on Fasting Blood Sugar Levels
  • 4.3Comparison with Control Group Results
  • 4.4Analysis of Variance in Blood Sugar Levels
  • 4.5Correlation Analysis between Dosage and Blood Sugar Levels
  • 4.6Discussion on Possible Mechanisms of Action
  • 4.7Interpretation of Results in Relation to Hypotheses
  • 4.8Implications of Findings for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Research Findings
  • 5.2Conclusions Drawn from the Study
  • 5.3Contributions to Existing Knowledge
  • 5.4Practical Applications and Recommendations
  • 5.5Areas for Future Research
  • 5.6Reflections on the Research Process
  • 5.7Limitations of the Study
  • 5.8Final Remarks and Acknowledgments

Thesis Abstract

This research work was carried out to determine the effect of Acanthus montanus on fasting blood sugar level of adult wistar rats. Twenty wistar rats (both male and female) weighing between 140g to 160g were used for this research project. They were acclimatized for 14 days after which the animals were grouped into four groups of five rats each. Each animal were administered based on their body weight. The dose given to animals in group A was 300mg/kg body weight of Acanthus montanus, Group B was given 500mg/kg body weight of Acanthus montanus, Group C was given 700mg/kg body weight of Acanthus montanus and group D (control group) was given distilled water. The administration lasted for thirteen days. A day before the animals were tested for fasting blood sugar level, food and water was withdrawn and they fasted for twelve hours. Blood samples were collected from the tail of the animals and the fasting blood sugar of each of the animals was tested.

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