Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats | Blazingprojects Postgraduate Thesis
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Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of the Study
  • 1.3Problem Statement
  • 1.4Objectives of the Study
  • 1.5Limitations of the Study
  • 1.6Scope of the Study
  • 1.7Significance of the Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Liver Functions
  • 2.2Allium Ascalonicum: Botanical Description
  • 2.3Traditional Uses of Allium Ascalonicum
  • 2.4Phytochemical Composition of Allium Ascalonicum
  • 2.5Pharmacological Properties of Allium Ascalonicum
  • 2.6Previous Studies on Allium Ascalonicum
  • 2.7Liver Function Tests (ASP, ALT, AST, Bilirubin)
  • 2.8Importance of Monitoring Liver Functions
  • 2.9Experimental Models for Liver Function Studies
  • 2.10Summary of the Literature Review

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Technique
  • 3.3Data Collection Methods
  • 3.4Ethical Considerations
  • 3.5Data Analysis Techniques
  • 3.6Variables and Measurements
  • 3.7Statistical Tools
  • 3.8Instrumentation

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Data Presentation and Analysis
  • 4.2Effects of Allium Ascalonicum Extract on Liver Functions
  • 4.3Comparison with Control Group
  • 4.4Interpretation of Results
  • 4.5Discussion on Findings
  • 4.6Implications of the Study
  • 4.7Recommendations for Future Research
  • 4.8Limitations of the Study

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions
  • 5.3Contributions to Knowledge
  • 5.4Practical Implications
  • 5.5Recommendations for Practice
  • 5.6Recommendations for Policy
  • 5.7Areas for Future Research
  • 5.8Closing Remarks

Thesis Abstract

The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).



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