Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats | Blazingprojects Postgraduate Thesis
Home / Biochemistry / Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Antioxidants
  • 2.2Superoxide Dismutase (SOD)
  • 2.3Catalase
  • 2.4Malondialdehyde (MDA)
  • 2.5Telferia Occidentalis and Antioxidants
  • 2.6Vernonia Amygdalina and Antioxidants
  • 2.7High Sucrose Diet and Health
  • 2.8Effects of Telferia Occidentalis on Antioxidants
  • 2.9Effects of Vernonia Amygdalina on Antioxidants
  • 2.10Comparative Analysis of Telferia Occidentalis and Vernonia Amygdalina

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Methodology Overview
  • 3.2Selection of Sample Population
  • 3.3Experimental Design
  • 3.4Data Collection Methods
  • 3.5Antioxidant Analysis Techniques
  • 3.6High Sucrose Diet Feeding Protocol
  • 3.7Statistical Analysis Methods
  • 3.8Ethical Considerations

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Findings
  • 4.2Effects of Telferia Occidentalis on SOD Levels
  • 4.3Effects of Telferia Occidentalis on Catalase Levels
  • 4.4Effects of Telferia Occidentalis on MDA Levels
  • 4.5Effects of Vernonia Amygdalina on SOD Levels
  • 4.6Effects of Vernonia Amygdalina on Catalase Levels
  • 4.7Effects of Vernonia Amygdalina on MDA Levels
  • 4.8Comparative Analysis of Telferia Occidentalis and Vernonia Amygdalina Effects

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary of Findings
  • 5.2Implications of Research
  • 5.3Recommendations for Future Research
  • 5.4Practical Applications of Study
  • 5.5Contributions to the Field of Antioxidant Research

Thesis Abstract

This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others were fed with normal rat chow. Antioxidant status were analysed in the brain, plasma and heart after four weeks of feeding. The result shows the imbalance caused by high sucrose diets having an effect on the antioxidants as the levels of superoxide dismutase, malondialdehyde and catalase in the liver, brain and plasma were significantly reduced (p<0.05). Therefore, moderate consumption of vegetable extracts can modulate antioxidant activity.

Thesis Overview

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