Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting dogs, leading to pain, reduced mobility, and impaired quality of life. Traditional treatment options for osteoarthritis in dogs have limitations in providing long-lasting relief. Stem cell therapy has emerged as a promising alternative for managing osteoarthritis by promoting tissue regeneration and reducing inflammation. This thesis explores the use of stem cell therapy in treating osteoarthritis in dogs, focusing on its efficacy, safety, and potential applications. Chapter One provides an introduction to the research topic, highlighting the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definitions of key terms. Chapter Two presents a comprehensive literature review covering ten key aspects related to stem cell therapy, osteoarthritis pathophysiology, current treatment modalities, and previous studies on stem cell therapy in veterinary medicine. Chapter Three outlines the research methodology, detailing the study design, participant selection criteria, stem cell isolation and characterization methods, treatment protocols, outcome measures, data analysis techniques, and ethical considerations. Chapter Four presents a detailed discussion of the research findings, including the efficacy of stem cell therapy in improving clinical outcomes, safety profile, potential mechanisms of action, and future directions for research and clinical practice. The conclusion and summary in Chapter Five provide a synthesis of the key findings, implications for veterinary practice, limitations of the study, and recommendations for future research. This thesis contributes to the growing body of knowledge on the use of stem cell therapy for managing osteoarthritis in dogs and highlights its potential as a novel treatment modality in veterinary medicine. The findings of this study have important implications for improving the quality of life and overall well-being of dogs suffering from osteoarthritis.

Thesis Overview

The research project titled "Exploring the use of stem cell therapy in treating osteoarthritis in dogs" aims to investigate the potential benefits and effectiveness of using stem cell therapy as a treatment for osteoarthritis in dogs. Osteoarthritis is a common degenerative joint disease in dogs, causing pain, stiffness, and reduced mobility, significantly impacting their quality of life. Traditional treatments such as pain medications and anti-inflammatory drugs may provide symptomatic relief but do not address the underlying joint damage. Stem cell therapy has emerged as a promising alternative approach to treating osteoarthritis in dogs. Stem cells have the unique ability to differentiate into various cell types, including cartilage cells, which could potentially regenerate damaged joint tissues. By exploring the use of stem cell therapy in dogs with osteoarthritis, this research seeks to evaluate its efficacy in relieving pain, improving joint function, and promoting cartilage repair. The research will involve a comprehensive literature review to gather existing knowledge on stem cell therapy for osteoarthritis in dogs, including its mechanisms of action, safety profile, and clinical outcomes. Additionally, the study will design and conduct experiments or clinical trials to assess the therapeutic potential of stem cell therapy in a canine model of osteoarthritis. Key aspects of the research will include defining the optimal source of stem cells, determining the most effective delivery method, evaluating the long-term effects of treatment, and assessing the overall safety and feasibility of stem cell therapy in dogs. The research will also consider factors such as patient selection criteria, treatment protocols, and post-treatment monitoring to ensure successful outcomes. Ultimately, this research aims to contribute valuable insights into the use of stem cell therapy as a novel treatment option for osteoarthritis in dogs. By elucidating the mechanisms of action and exploring the therapeutic benefits of stem cells in joint repair and regeneration, this study seeks to advance veterinary medicine and improve the management of osteoarthritis in canine patients.