Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting dogs, leading to pain, reduced mobility, and decreased quality of life. Conventional treatments such as pain management and physical therapy provide symptomatic relief but do not address the underlying cause of the disease. Stem cell therapy has emerged as a promising alternative approach for treating osteoarthritis in dogs by promoting tissue regeneration and reducing inflammation. This thesis explores the use of stem cell therapy in treating osteoarthritis in dogs, focusing on its efficacy, safety, and long-term outcomes. Chapter One provides an introduction to the topic, discussing the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms. The literature review in Chapter Two examines ten key studies on stem cell therapy for osteoarthritis in dogs, highlighting the current state of knowledge in this field. Chapter Three outlines the research methodology, including the selection of study subjects, stem cell isolation and characterization, treatment protocols, outcome measures, and statistical analysis. The chapter also discusses ethical considerations and potential biases that may impact the study results. Chapter Four presents a detailed discussion of the findings, including the efficacy of stem cell therapy in improving clinical signs, joint function, and quality of life in dogs with osteoarthritis. The chapter also explores the safety profile of this treatment modality and discusses potential factors influencing treatment outcomes. Finally, Chapter Five summarizes the key findings of the study and offers conclusions based on the results obtained. The thesis concludes with recommendations for future research directions and clinical applications of stem cell therapy in the management of osteoarthritis in dogs. Overall, this thesis contributes to the growing body of evidence supporting the use of stem cell therapy as a promising treatment option for osteoarthritis in dogs. By exploring the safety and efficacy of this innovative approach, this research aims to improve the quality of life for dogs suffering from this debilitating condition.

Thesis Overview

The project titled "Exploring the Use of Stem Cell Therapy in Treating Osteoarthritis in Dogs" aims to investigate the potential benefits and effectiveness of utilizing stem cell therapy as a treatment for osteoarthritis in dogs. Osteoarthritis is a common degenerative joint disease in dogs that causes pain, stiffness, and reduced mobility, significantly impacting their quality of life. Traditional treatment options for osteoarthritis in dogs, such as pain medications and anti-inflammatory drugs, may provide symptomatic relief but do not address the underlying cause of the disease. Stem cell therapy offers a promising alternative approach by harnessing the regenerative properties of stem cells to repair damaged tissues and promote healing within the joints. Stem cells have the potential to differentiate into various cell types, including cartilage and bone cells, which are crucial for repairing the damaged joint structures in osteoarthritic dogs. By introducing stem cells into the affected joints, this therapy aims to not only alleviate pain and inflammation but also to stimulate tissue regeneration and slow down the progression of osteoarthritis. This research project will involve a comprehensive literature review to gather existing knowledge on the use of stem cell therapy in veterinary medicine, particularly in the treatment of osteoarthritis in dogs. The literature review will explore the mechanisms of action of stem cells, different sources of stem cells, methods of administration, and documented outcomes in canine osteoarthritis cases. By synthesizing the available evidence, this study aims to provide a solid foundation for understanding the potential benefits and limitations of stem cell therapy in treating osteoarthritis in dogs. Furthermore, the research methodology will involve conducting experimental studies to evaluate the efficacy and safety of stem cell therapy in a controlled setting. Dogs diagnosed with osteoarthritis will be selected as study subjects, and they will undergo stem cell treatment under close monitoring. Clinical assessments, such as physical examinations, gait analysis, and imaging studies, will be used to evaluate the treatment outcomes over a specified period. The research will also explore factors influencing the success of stem cell therapy, such as the optimal dosage, frequency of treatment, and long-term effects on joint health. The findings from this research project have the potential to significantly advance the field of veterinary medicine by providing valuable insights into the use of stem cell therapy for managing osteoarthritis in dogs. If successful, this innovative treatment approach could offer a more effective and sustainable solution for alleviating pain and improving the quality of life for canine patients suffering from osteoarthritis. Ultimately, this research aims to contribute to the development of novel therapeutic strategies that enhance the well-being and longevity of companion animals affected by degenerative joint diseases.