Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting both humans and animals, including dogs. Traditional treatments for osteoarthritis in dogs often focus on managing symptoms and providing pain relief, but they do not address the underlying cause of the disease. Stem cell therapy has emerged as a promising treatment modality for osteoarthritis due to its regenerative potential and ability to modulate the inflammatory response within the joints. This thesis aims to investigate the effectiveness of stem cell therapy in treating osteoarthritis in dogs. Chapter One provides an introduction to the research topic, including the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. Chapter Two presents a comprehensive literature review covering ten key aspects related to osteoarthritis, stem cell therapy, and previous studies on the use of stem cells in treating osteoarthritis in dogs. Chapter Three outlines the research methodology, including the study design, sample selection, stem cell isolation and preparation, treatment protocol, outcome measures, data collection methods, and statistical analysis plan. The chapter also describes ethical considerations and potential limitations of the research methodology. Chapter Four presents the findings of the study, including the clinical outcomes of stem cell therapy in dogs with osteoarthritis, changes in joint function, pain scores, inflammatory markers, and radiographic assessments. The chapter discusses the implications of the results, compares them to existing literature, and highlights any significant findings or limitations. Chapter Five offers a conclusion and summary of the thesis, emphasizing the key findings, implications for veterinary practice, recommendations for future research, and overall contributions to the field of veterinary medicine. The thesis concludes with a reflection on the potential of stem cell therapy as a viable treatment option for osteoarthritis in dogs and the importance of further research in this area to improve the quality of life for canine patients. Keywords osteoarthritis, dogs, stem cell therapy, effectiveness, regenerative medicine, veterinary medicine.

Thesis Overview

Overview: The project titled "Investigation of the effectiveness of stem cell therapy in treating osteoarthritis in dogs" aims to explore the potential of stem cell therapy as a novel treatment approach for osteoarthritis in dogs. Osteoarthritis is a common degenerative joint disease in dogs, characterized by joint pain, stiffness, and decreased mobility. Current treatment options for osteoarthritis in dogs are limited and often focus on managing symptoms rather than addressing the underlying cause of the disease. Stem cell therapy offers a promising alternative by targeting the damaged joint tissues and promoting regeneration. Research Objectives: 1. To review the existing literature on osteoarthritis in dogs and the potential benefits of stem cell therapy. 2. To investigate the effectiveness of stem cell therapy in reducing joint pain and improving mobility in dogs with osteoarthritis. 3. To assess the safety and long-term effects of stem cell therapy in treating osteoarthritis in dogs. 4. To compare the outcomes of stem cell therapy with traditional treatment approaches for osteoarthritis in dogs. 5. To identify any limitations or challenges associated with the use of stem cell therapy in dogs with osteoarthritis. Methodology: The research will involve a comprehensive literature review to gather existing knowledge on osteoarthritis in dogs and the use of stem cell therapy in veterinary medicine. A clinical study will be conducted on a sample of dogs diagnosed with osteoarthritis, where they will receive stem cell therapy as the experimental treatment. The dogs will be monitored for changes in joint pain, mobility, and overall quality of life over a specified period. Data analysis will be performed to compare the outcomes of stem cell therapy with conventional treatment methods. Significance: This research is significant as it has the potential to provide valuable insights into the use of stem cell therapy for treating osteoarthritis in dogs. If the results demonstrate positive outcomes, it could lead to the development of more effective and targeted treatment options for this common degenerative joint disease in dogs. Additionally, the findings of this study may contribute to advancing veterinary medicine and improving the quality of life for dogs suffering from osteoarthritis. Conclusion: The investigation of the effectiveness of stem cell therapy in treating osteoarthritis in dogs is a critical step towards addressing the limitations of current treatment options and exploring innovative approaches to managing this debilitating condition in canine patients. By combining scientific research with clinical practice, this project aims to bridge the gap between theory and application, ultimately benefiting both veterinary professionals and their canine patients.