Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting canines, leading to pain, reduced mobility, and decreased quality of life. Current treatment options often provide limited relief and are not curative. Stem cell therapy has emerged as a promising alternative for managing osteoarthritis due to its regenerative potential. This thesis aims to explore the use of stem cell therapy in treating canine osteoarthritis, focusing on its effectiveness, safety, and long-term outcomes. Chapter 1 introduces the background of the study, highlighting the prevalence and impact of osteoarthritis in canines. The problem statement emphasizes the limitations of current treatment modalities and the need for more effective therapeutic approaches. The objectives of the study include evaluating the efficacy of stem cell therapy, identifying its limitations, and assessing the scope and significance of its application in veterinary medicine. The structure of the thesis provides a roadmap for the subsequent chapters, while the definition of terms clarifies key concepts and terminology used throughout the research. Chapter 2 presents a comprehensive literature review, encompassing ten key areas related to stem cell therapy in veterinary medicine, osteoarthritis pathophysiology, and treatment modalities. This section aims to contextualize the current understanding of stem cell therapy and its potential applications in the field of veterinary orthopedics. Chapter 3 outlines the research methodology, detailing the study design, sample selection criteria, stem cell isolation and characterization methods, treatment protocols, and outcome assessment strategies. This chapter also includes ethical considerations, data analysis techniques, and quality control measures to ensure the validity and reliability of the study findings. Chapter 4 discusses the findings of the research, presenting the efficacy of stem cell therapy in treating canine osteoarthritis based on clinical outcomes, biomarker analysis, and histological evaluations. The limitations of the study are acknowledged, and potential areas for further research are identified to enhance the understanding of stem cell therapy in veterinary orthopedics. Chapter 5 provides a conclusion and summary of the thesis, highlighting the key findings, implications for clinical practice, and recommendations for future research. This section underscores the potential of stem cell therapy as a promising treatment modality for canine osteoarthritis and emphasizes the importance of continued research in this field to optimize therapeutic outcomes and improve the quality of life for affected animals. In conclusion, this thesis contributes to the growing body of knowledge on stem cell therapy in veterinary medicine and provides valuable insights into its application for treating canine osteoarthritis. By elucidating the efficacy, safety, and long-term benefits of this innovative therapeutic approach, the study aims to advance veterinary orthopedics and enhance the well-being of canine patients suffering from osteoarthritis.

Thesis Overview

The research project titled "Exploring the Use of Stem Cell Therapy in Treating Canine Osteoarthritis" focuses on investigating the potential benefits and applications of stem cell therapy in the treatment of osteoarthritis in dogs. Osteoarthritis, a common degenerative joint disease in canines, results in pain, stiffness, and reduced mobility, significantly impacting the quality of life of affected animals. Traditional treatment options for osteoarthritis in dogs often provide only symptomatic relief and do not address the underlying causes of the disease. Stem cell therapy has emerged as a promising regenerative medicine approach that aims to repair damaged tissues, reduce inflammation, and promote healing in osteoarthritic joints. By utilizing the regenerative properties of stem cells, this therapy offers the potential to not only alleviate symptoms but also to potentially slow down or even reverse the progression of osteoarthritis in dogs. This research project will delve into the mechanisms of action of stem cell therapy in the context of canine osteoarthritis, exploring how stem cells can modulate the inflammatory response, promote tissue regeneration, and enhance joint function. The study will also investigate the safety, efficacy, and long-term outcomes of stem cell therapy in treating osteoarthritis in dogs through a comprehensive review of existing literature, case studies, and clinical trials. Furthermore, the project aims to evaluate the practical aspects of implementing stem cell therapy in veterinary clinics, including considerations such as patient selection, treatment protocols, monitoring of outcomes, and cost-effectiveness. By shedding light on the current state of knowledge and ongoing research in this field, this project seeks to contribute valuable insights that can inform veterinary practitioners, researchers, and pet owners on the potential of stem cell therapy as a novel approach to managing osteoarthritis in dogs. Overall, "Exploring the Use of Stem Cell Therapy in Treating Canine Osteoarthritis" represents a significant endeavor to advance our understanding of regenerative medicine applications in veterinary care, with the ultimate goal of improving the health and well-being of canine patients suffering from osteoarthritis.