Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease in dogs, leading to pain and decreased mobility. Stem cell therapy has emerged as a promising treatment option for osteoarthritis in canines, showing potential for tissue regeneration and anti-inflammatory effects. This thesis investigates the efficacy of stem cell therapy in treating osteoarthritis in dogs, aiming to provide valuable insights into its therapeutic benefits and limitations. The study begins with a comprehensive review of the literature on osteoarthritis in dogs, including its etiology, pathophysiology, and current treatment options. It explores the role of stem cells in regenerative medicine and their potential application in managing osteoarthritis. The research methodology encompasses a detailed description of the experimental design, sample selection, stem cell sources, treatment protocols, and outcome measures utilized in the study. Results from the investigation are presented in Chapter Four, analyzing the effectiveness of stem cell therapy in alleviating osteoarthritis symptoms, improving joint function, and reducing inflammatory markers in canine subjects. The discussion delves into the implications of these findings, highlighting the strengths and limitations of stem cell therapy as a treatment modality for osteoarthritis in dogs. In conclusion, this thesis provides a critical evaluation of the efficacy of stem cell therapy in treating osteoarthritis in dogs, shedding light on its potential as a regenerative medicine approach for joint disease management. The study contributes to the growing body of research on stem cell therapy applications in veterinary medicine and underscores the importance of further investigations to optimize treatment outcomes and ensure the welfare of canine patients with osteoarthritis.

Thesis Overview

The research project titled "Investigation of the efficacy of stem cell therapy in treating osteoarthritis in dogs" aims to explore the potential benefits and limitations of using stem cell therapy as a treatment option for osteoarthritis in dogs. Osteoarthritis is a degenerative joint disease that commonly affects aging dogs, leading to pain, stiffness, and decreased mobility. Current treatment options for osteoarthritis in dogs often focus on managing symptoms rather than addressing the underlying cause of the disease. Stem cell therapy has emerged as a promising regenerative medicine approach that harnesses the regenerative potential of stem cells to promote tissue repair and regeneration. In the context of osteoarthritis, stem cell therapy holds the potential to not only alleviate symptoms but also to repair damaged joint tissues and slow down disease progression. However, the efficacy of stem cell therapy in treating osteoarthritis in dogs remains a subject of ongoing research and debate. This research overview will delve into the rationale behind investigating stem cell therapy for osteoarthritis in dogs, discussing the current understanding of the disease, the mechanisms of action of stem cell therapy, and the existing evidence supporting its efficacy. The project will involve a comprehensive review of the scientific literature to evaluate the outcomes of previous studies and clinical trials that have explored the use of stem cell therapy in canine osteoarthritis. Furthermore, the research will detail the methodology to be employed, including the selection of appropriate stem cell sources, the administration route, dosages, and follow-up assessments. It will also address ethical considerations, potential risks, and regulatory aspects associated with stem cell therapy in veterinary medicine. By conducting this investigation, the project aims to contribute valuable insights into the feasibility and effectiveness of stem cell therapy as a treatment modality for osteoarthritis in dogs. The findings of this research have the potential to inform veterinary practitioners, researchers, and pet owners about the role of stem cell therapy in improving the quality of life for dogs suffering from osteoarthritis. Ultimately, this project aspires to advance our understanding of regenerative medicine applications in veterinary orthopedics and pave the way for novel therapeutic strategies to enhance the well-being of canine patients with osteoarthritis.