Thesis Abstract

Abstract
Tendon injuries are common in equines and often present significant challenges in terms of treatment and recovery. Traditional treatment methods have shown limited success in achieving full functional recovery, leading to a growing interest in alternative therapies such as stem cell therapy. This thesis explores the potential role of stem cell therapy in treating tendon injuries in equines. The introduction sets the stage by providing an overview of the background of the study, highlighting the prevalence of tendon injuries in equines and the limitations of current treatment methods. The problem statement identifies the gaps in existing knowledge and the need for alternative treatment approaches. The objectives of the study are outlined to investigate the effectiveness of stem cell therapy in promoting tendon healing and functional recovery in equines. The limitations and scope of the study are discussed to provide clarity on the boundaries and potential constraints of the research. The significance of the study is underscored, emphasizing the potential impact of the findings on equine healthcare and welfare. Chapter two presents a comprehensive literature review that delves into existing research on tendon injuries, stem cell therapy, and equine healthcare. The review synthesizes key findings, identifies trends and gaps in the literature, and lays the foundation for the research methodology. Chapter three details the research methodology, including the study design, sample selection, stem cell administration protocols, outcome measures, and data analysis techniques. The methodology is structured to ensure the rigor and reliability of the study findings. Chapter four presents the discussion of findings, analyzing the outcomes of the stem cell therapy intervention in equines with tendon injuries. The results are interpreted in the context of existing literature, highlighting the potential benefits and limitations of stem cell therapy in equine tendon healing. Finally, chapter five provides a conclusion and summary of the thesis, summarizing the key findings, discussing their implications, and suggesting avenues for future research. The thesis contributes to the growing body of knowledge on equine healthcare and offers insights into the potential role of stem cell therapy in enhancing tendon healing and functional recovery in equines.

Thesis Overview

The project titled "Exploring the Role of Stem Cell Therapy in Treating Tendon Injuries in Equines" aims to investigate the potential benefits and limitations of utilizing stem cell therapy for treating tendon injuries in horses. Tendon injuries are a common problem in equine athletes, often leading to significant performance limitations and long recovery periods. Traditional treatment methods have shown varying degrees of success, highlighting the need for alternative approaches to enhance healing and improve outcomes in equine patients. Stem cell therapy has emerged as a promising regenerative medicine strategy for treating various musculoskeletal conditions, including tendon injuries. Stem cells possess unique properties that enable them to differentiate into different cell types and promote tissue repair and regeneration. By harnessing the regenerative potential of stem cells, it is hypothesized that this therapy could accelerate tendon healing, reduce scar tissue formation, and improve the overall functional outcome in horses with tendon injuries. The research will involve a comprehensive literature review to explore the current understanding of tendon injuries in horses, the principles of stem cell biology, and the existing evidence on the use of stem cell therapy in equine medicine. This review will provide a solid foundation for understanding the mechanisms of action, safety profile, and efficacy of stem cell therapy in tendon healing. Furthermore, the project will include experimental studies to assess the therapeutic potential of stem cell therapy in a controlled equine model of tendon injury. Through a combination of in vitro and in vivo experiments, the research aims to evaluate the impact of stem cell treatment on tendon healing parameters such as tissue regeneration, inflammation, biomechanical properties, and functional recovery in injured tendons. The findings from this research will contribute valuable insights into the feasibility and effectiveness of stem cell therapy as a treatment modality for tendon injuries in horses. By elucidating the underlying mechanisms of action and evaluating the clinical outcomes of stem cell therapy in equine patients, this study seeks to advance our understanding of regenerative medicine approaches for enhancing tendon healing and improving the welfare of equine athletes.