Thesis Abstract

Abstract
This thesis investigates the potential benefits and efficacy of utilizing stem cell therapy in the treatment of osteoarthritis in canines. Osteoarthritis is a common degenerative joint disease that affects dogs, leading to pain, discomfort, and decreased mobility. Stem cell therapy has emerged as a promising treatment approach due to its regenerative and anti-inflammatory properties. The primary aim of this study is to evaluate the effectiveness of stem cell therapy in alleviating symptoms and improving joint function in dogs with osteoarthritis. The introduction provides a comprehensive overview of osteoarthritis in canines, highlighting its prevalence, clinical manifestations, and current treatment options. The background of the study delves into the underlying pathophysiology of osteoarthritis, emphasizing the role of inflammation and cartilage degeneration in disease progression. The problem statement identifies the limitations of conventional treatments and underscores the need for alternative therapeutic strategies. The objectives of the study are outlined to investigate the impact of stem cell therapy on pain reduction, joint function improvement, and cartilage regeneration in dogs with osteoarthritis. The limitations of the study are acknowledged, including potential variability in treatment outcomes and the need for long-term follow-up assessments. The scope of the study is defined in terms of the specific inclusion criteria for canine patients and the type of stem cell therapy being utilized. The significance of the study lies in its potential to advance the field of veterinary medicine by providing valuable insights into the efficacy of stem cell therapy for osteoarthritis in canines. The structure of the thesis is outlined to guide the reader through the subsequent chapters, including the literature review, research methodology, discussion of findings, and conclusion. The literature review critically examines existing research on stem cell therapy for osteoarthritis in both human and animal models. Key findings related to the mechanisms of action, safety profile, and clinical outcomes of stem cell therapy are synthesized to inform the current study. The research methodology details the study design, sample selection, treatment protocol, outcome measures, and statistical analysis methods employed in the investigation. Chapter four presents a detailed discussion of the study findings, including the evaluation of pain scores, joint function assessments, and imaging studies in canine patients undergoing stem cell therapy. The implications of the results are discussed in relation to the potential benefits and challenges of implementing stem cell therapy in veterinary practice. In conclusion, this thesis provides valuable insights into the use of stem cell therapy as a novel approach for treating osteoarthritis in canines. The findings support the potential of stem cell therapy to improve clinical outcomes and enhance the quality of life for dogs suffering from this debilitating condition. Recommendations for future research and clinical applications of stem cell therapy in veterinary medicine are also discussed. Keywords stem cell therapy, osteoarthritis, canine, regenerative medicine, joint disease, veterinary medicine.

Thesis Overview