Thesis Abstract

Abstract
Breast cancer is one of the most prevalent cancers affecting women worldwide, and early detection is crucial for successful treatment outcomes. Mammography has been the standard imaging modality for breast cancer screening for decades, but recent advancements have introduced Digital Breast Tomosynthesis (DBT) as a potential alternative with improved diagnostic capabilities. This study aims to conduct a comparative analysis of the diagnostic accuracy between 2D Mammography and Digital Breast Tomosynthesis in breast cancer screening. The research begins with a comprehensive review of the literature to examine existing studies and evidence regarding the effectiveness of both imaging modalities in detecting breast cancer. The literature review encompasses ten key areas, including the principles of mammography and DBT, comparative studies on diagnostic accuracy, limitations of each technique, and advancements in breast cancer screening technology. The methodology section outlines the research design, participant selection criteria, imaging protocols, data analysis techniques, and statistical methods employed in the comparative analysis. This chapter also discusses ethical considerations, potential biases, and strategies to ensure the reliability and validity of the study results. The findings chapter presents the results of the comparative analysis, including sensitivity, specificity, positive predictive value, negative predictive value, and overall diagnostic accuracy of 2D Mammography and Digital Breast Tomosynthesis. The discussion delves into the implications of the findings, potential reasons for any observed differences in diagnostic accuracy, and recommendations for clinical practice and future research. In conclusion, this thesis provides valuable insights into the comparative diagnostic accuracy of 2D Mammography and Digital Breast Tomosynthesis in breast cancer screening. The study findings contribute to the growing body of evidence on the effectiveness of these imaging modalities and offer guidance to healthcare professionals in selecting the most appropriate screening method for improved patient outcomes.

Thesis Overview

The research project titled "Comparative Analysis of Diagnostic Accuracy between 2D Mammography and Digital Breast Tomosynthesis in Breast Cancer Screening" aims to investigate and compare the diagnostic accuracy of two commonly used imaging techniques in breast cancer screening. Mammography has been the gold standard for breast cancer detection for many years, but advancements in technology have introduced digital breast tomosynthesis as a promising alternative with potential benefits. The research will start with a comprehensive introduction highlighting the significance of breast cancer screening, the evolution of imaging techniques, and the importance of accurate diagnosis in improving patient outcomes. The background of the study will provide a detailed overview of 2D mammography and digital breast tomosynthesis, including their principles, advantages, and limitations. The problem statement will address the existing gap in knowledge regarding the comparative diagnostic accuracy of these two imaging modalities, emphasizing the need for empirical research to guide clinical decision-making. The research objectives will be clearly defined, focusing on evaluating and comparing the sensitivity, specificity, and overall accuracy of 2D mammography and digital breast tomosynthesis in detecting breast cancer. Limitations of the study, such as sample size constraints, potential biases, and technical challenges, will be acknowledged to ensure the transparency and validity of the research findings. The scope of the study will outline the specific parameters, inclusion criteria, and methodology adopted to achieve the research objectives effectively. The significance of the study lies in its potential to contribute valuable insights to the field of radiography and breast cancer screening by providing evidence-based recommendations for clinical practice. The structure of the thesis will be outlined, detailing the organization of chapters and the flow of information to facilitate a coherent and logical presentation of the research findings. Additionally, a comprehensive definition of key terms and concepts related to breast cancer screening, mammography, and digital breast tomosynthesis will be provided to ensure clarity and understanding throughout the research project. Overall, this research aims to address a critical gap in knowledge by conducting a comparative analysis of the diagnostic accuracy between 2D mammography and digital breast tomosynthesis in breast cancer screening. Through rigorous methodology and robust data analysis, the findings of this study have the potential to impact clinical practice, improve patient outcomes, and guide future research in the field of radiography and breast cancer detection.