Thesis Abstract

Abstract
The increasing threat of antibiotic resistance poses a significant challenge to global public health. In the face of this crisis, alternative treatment options are urgently needed. Bacteriophages, viruses that infect and kill bacteria, have emerged as a promising avenue for combating antibiotic-resistant infections. This thesis explores the potential of bacteriophages as an alternative therapy for antibiotic-resistant infections. Chapter One provides an introduction to the research topic, presenting the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definitions of key terms. Chapter Two conducts a comprehensive literature review, examining ten key studies that investigate the efficacy of bacteriophages in treating antibiotic-resistant infections. Chapter Three outlines the research methodology employed in this study. It discusses the research design, sampling techniques, data collection methods, data analysis procedures, ethical considerations, and limitations of the methodology. The chapter also details the selection criteria for bacteriophages and bacterial strains used in the experimental procedures. In Chapter Four, the findings of the research are presented and discussed in detail. The efficacy of bacteriophages in targeting and killing antibiotic-resistant bacteria is evaluated, along with factors influencing their effectiveness, such as host range and resistance mechanisms. The chapter also explores the potential challenges and limitations of using bacteriophages as a therapeutic option. Chapter Five offers a conclusion and summary of the thesis, highlighting key findings, implications for future research, and recommendations for the application of bacteriophages in clinical settings. The study underscores the significant potential of bacteriophages as a viable alternative therapy for antibiotic-resistant infections and underscores the importance of further research in this field to address the growing threat of antibiotic resistance. In conclusion, this thesis contributes to the growing body of knowledge on bacteriophages as a novel treatment strategy for antibiotic-resistant infections. By shedding light on the potential benefits and challenges associated with using bacteriophages in clinical practice, this research aims to provide valuable insights for healthcare professionals, researchers, and policymakers working to combat the global crisis of antibiotic resistance.

Thesis Overview

The research project titled "Exploring the potential of bacteriophages as an alternative therapy for antibiotic-resistant infections" aims to investigate the efficacy and potential applications of bacteriophages as a novel alternative therapy for combating antibiotic-resistant infections. In recent years, the rise of antibiotic resistance has become a major global health concern, posing a significant threat to public health. Traditional antibiotics are becoming less effective due to the emergence of multidrug-resistant bacteria, leading to an urgent need for new therapeutic strategies. Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering a promising alternative to antibiotics for treating infections. The research will begin with a comprehensive literature review to examine the current understanding of bacteriophages, their mechanisms of action, and their historical use in treating bacterial infections. This review will also explore the challenges associated with antibiotic resistance and the potential advantages of using phage therapy as an alternative approach. The methodology section will outline the experimental design and procedures for evaluating the efficacy of phage therapy in treating antibiotic-resistant bacterial strains. This will involve isolating and characterizing bacteriophages, conducting in vitro and in vivo studies to assess their ability to kill target bacteria, and evaluating their safety and potential for clinical application. The findings from the study will be discussed in detail, highlighting the effectiveness of phage therapy in targeting and eliminating antibiotic-resistant bacteria. The results will also address any limitations or challenges encountered during the research process and provide insights into the future potential of bacteriophages as a viable alternative therapy for combating antibiotic resistance. In conclusion, this research project seeks to contribute valuable insights into the potential of bacteriophages as an alternative therapy for antibiotic-resistant infections. By exploring the unique properties and mechanisms of action of phages, this study aims to pave the way for the development of innovative and effective treatment strategies to address the growing threat of antibiotic resistance in healthcare settings.