Thesis Abstract

Abstract
The escalating global issue of antibiotic resistance poses a significant threat to public health, necessitating innovative approaches to combat multidrug-resistant bacterial infections. This thesis investigates the antimicrobial properties of plant extracts as potential alternatives to conventional antibiotics in the fight against antibiotic-resistant bacteria. The study focuses on exploring the efficacy of various plant extracts in inhibiting the growth of antibiotic-resistant bacterial strains through in vitro experiments and elucidating the underlying mechanisms of action. Chapter One provides an introductory overview of the research, outlining the background of the study, defining the problem statement, stating the objectives, discussing the limitations and scope of the study, highlighting its significance, and presenting the structure of the thesis. The chapter also includes a comprehensive definition of key terms to enhance understanding. Chapter Two presents a detailed literature review encompassing ten key aspects related to antibiotic resistance, plant extracts with antimicrobial properties, mechanisms of antibiotic resistance, and previous studies on the use of plant extracts against antibiotic-resistant bacteria. This review synthesizes existing knowledge and identifies gaps in the current literature that the present study aims to address. Chapter Three delineates the research methodology employed in this study, covering various aspects such as the selection and preparation of plant extracts, bacterial strains used, experimental procedures for antimicrobial testing, data analysis methods, and quality control measures. The chapter provides a robust framework for conducting the experiments and ensures the reliability and validity of the study results. Chapter Four presents a comprehensive discussion of the findings derived from the experimental investigations. The results of the antimicrobial assays conducted with different plant extracts against antibiotic-resistant bacterial strains are analyzed and interpreted in detail. The chapter also explores the potential mechanisms of action by which the plant extracts exert their antimicrobial effects, shedding light on their therapeutic potential as alternative antimicrobial agents. Chapter Five encapsulates the conclusion and summary of the project thesis, highlighting the key findings, implications, and contributions to the field of microbiology. The chapter discusses the significance of the study results in the context of combating antibiotic resistance and suggests future research directions to further explore the therapeutic applications of plant extracts against antibiotic-resistant bacteria. In conclusion, this thesis contributes valuable insights into the antimicrobial properties of plant extracts as promising candidates for combating antibiotic-resistant bacteria. The findings of this study have significant implications for the development of novel antimicrobial agents and strategies to address the pressing global challenge of antibiotic resistance.

Thesis Overview