Thesis Abstract

Abstract
The constant threat posed by infectious diseases highlights the urgent need for rapid and accurate diagnostic tools to facilitate timely and effective disease management. This thesis presents the development of a novel Rapid Diagnostic Test (RDT) for infectious diseases, aiming to address the current limitations of existing diagnostic methods. The project encompasses a comprehensive investigation into the design, development, and validation of the RDT, with a focus on improving diagnostic accuracy, speed, and simplicity. The introduction provides an overview of the significance of rapid diagnostic tests in infectious disease management, highlighting the critical role they play in early detection, treatment initiation, and disease control. The background of the study delves into the current challenges faced in diagnosing infectious diseases, emphasizing the limitations of conventional diagnostic methods and the need for innovative solutions. The problem statement identifies the gaps in existing diagnostic technologies and sets the context for the development of the RDT. The objectives of the study are outlined to guide the research process, including the design and optimization of the RDT platform, the selection and validation of target biomarkers, and the evaluation of the test performance. Limitations of the study are acknowledged, such as constraints in resources, time, and access to specific disease samples. The scope of the study defines the focus areas and boundaries of the research, outlining the infectious diseases targeted and the intended applications of the RDT. The significance of the study is emphasized in terms of its potential impact on public health, clinical practice, and disease surveillance. The structure of the thesis provides a roadmap for the reader, outlining the organization of chapters and key sections. Definitions of essential terms are provided to ensure clarity and understanding of technical terminology used throughout the thesis. The literature review explores existing research and technologies related to rapid diagnostic tests for infectious diseases, highlighting the strengths, weaknesses, and gaps in current approaches. Key findings from the literature inform the design and development of the RDT, guiding the selection of detection methods, biomarkers, and assay formats. The research methodology details the experimental approach and techniques employed in developing the RDT, including the selection of materials, fabrication of test components, optimization of assay conditions, and validation of test performance. The methodology also addresses quality control measures, data analysis techniques, and ethical considerations. The discussion of findings presents the results of the RDT development process, including the performance characteristics, sensitivity, specificity, and reproducibility of the test. The interpretation of results considers the implications for disease diagnosis, surveillance, and treatment, highlighting the strengths and limitations of the developed RDT. In conclusion, this thesis summarizes the key findings, contributions, and implications of the study on the development of a Rapid Diagnostic Test for infectious diseases. The potential applications of the RDT in clinical practice, public health, and disease control are discussed, emphasizing the importance of rapid and accurate diagnostic tools in combating infectious diseases. Overall, this research contributes to the advancement of diagnostic technologies and holds promise for improving disease management and patient outcomes.

Thesis Overview