Thesis Abstract

Abstract
This thesis investigates the impact of probiotics on gut health in individuals with Irritable Bowel Syndrome (IBS) through a systematic review and meta-analysis. The study aims to provide a comprehensive analysis of the existing literature on the use of probiotics as a potential treatment option for IBS, focusing on their effectiveness in improving gut health and alleviating symptoms associated with this common gastrointestinal disorder. The research methodology involves a systematic review of relevant studies and a meta-analysis to synthesize the findings and draw meaningful conclusions. Chapter 1 provides the introductory framework for the study, including the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. The chapter also includes the definition of key terms to establish a clear understanding of the subject matter. Chapter 2 presents a detailed literature review consisting of ten key components that explore the current state of knowledge on probiotics and their impact on gut health in individuals with IBS. The review encompasses studies that have investigated the efficacy of probiotics in managing IBS symptoms and improving overall gastrointestinal well-being. Chapter 3 outlines the research methodology employed in this study, including the research design, data collection methods, sample selection criteria, data analysis techniques, and quality assessment measures. This chapter provides insight into the systematic approach used to review and analyze the relevant literature on probiotics and gut health in the context of IBS. Chapter 4 delves into a comprehensive discussion of the findings derived from the systematic review and meta-analysis. The chapter highlights the key outcomes, trends, and patterns identified in the literature, shedding light on the efficacy of probiotics as a therapeutic intervention for individuals with IBS. The discussion also addresses any discrepancies or limitations observed in the reviewed studies. Chapter 5 serves as the concluding section of the thesis, summarizing the main findings, implications, and recommendations arising from the study. The chapter offers insights into the potential benefits of probiotics in improving gut health and managing symptoms of IBS, as well as suggestions for future research directions in this area. Overall, this thesis contributes to the growing body of knowledge on the role of probiotics in enhancing gut health and addressing the challenges faced by individuals with Irritable Bowel Syndrome. The systematic review and meta-analysis conducted in this study offer valuable insights into the potential benefits of probiotic supplementation as a complementary therapy for individuals living with IBS, paving the way for further research and clinical applications in this field.

Thesis Overview

The project titled "The Impact of Probiotics on Gut Health in Individuals with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis" aims to explore the effectiveness of probiotics in improving gut health among individuals diagnosed with Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a common gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. Probiotics are live microorganisms that are believed to provide health benefits when consumed in adequate amounts. The research project will conduct a systematic review and meta-analysis of existing studies to examine the impact of probiotics on gut health in individuals with IBS. The systematic review will involve a comprehensive search of relevant literature in databases such as PubMed, Cochrane Library, and Scopus to identify randomized controlled trials and observational studies that investigate the use of probiotics in managing IBS symptoms. The meta-analysis will involve the statistical synthesis of data from selected studies to evaluate the overall effect of probiotics on gut health outcomes in individuals with IBS. Key outcomes of interest will include changes in gastrointestinal symptoms, such as abdominal pain, bloating, and stool consistency, as well as improvements in overall quality of life and psychological well-being. Through this research project, we aim to provide a comprehensive overview of the current evidence regarding the use of probiotics in the management of IBS. The findings of this study will contribute to the existing body of knowledge on the topic and may have implications for clinical practice, guiding healthcare providers in the use of probiotics as a potential therapeutic option for individuals with IBS. Overall, this research project seeks to advance our understanding of the impact of probiotics on gut health in individuals with Irritable Bowel Syndrome and to provide valuable insights that may inform future research and clinical practice in the field of gastroenterology and nutrition.