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</p><p>Title<br>Page – – – – – – – – – – i</p><p>Declaration – – – – – – – – – – ii</p><p>Certification – – – – – – – – – – iii</p><p>Dedication – – – – – – – – – – iv</p><p>Acknowledgements – – – – – – – – – v</p><p>Table<br>of contents – – – – – – – – – vi</p><p>Abstract – – – – – – – – – – xi</p><p><b>
Chapter ONE
: INTRODUCTION</b></p><p>1.1 <br>Background of Study – – – – – – – 1</p><p>1.2 <br>Objective of Study- – – – – – – – – 4</p><p>1.3 <br>Justification/Rationale for the Study- – – – – – 4</p><p>1.5 Significance<br>of the Study- – – – – – – 6</p><p><b>
Chapter TWO
: LITERATURE<br>REVIEW</b></p><p>2.1 <br>Cannabis Sativa Plant Description- – – – – – 6</p><p>2.1.1 <br>Seedling:- – – – – – – – – – 7</p><p>2.1.2 <br>Stem: – – – – – – – – – – 7</p><p>2.1.3 <br>Leaves:- – – – – – – – – – 7</p><p>2.1.4 <br>Buds or flowers on the cannabis plant:- – – – – 7</p><p>2.1.5 <br>Smell of the cannabis plant, especially the leaves and flowers- – 8</p><p>2.1.6 <br>Discovery and cultivation- – – – – – – 8</p><p>2.2 Scientific<br>Classification of Cannabis- – – – – – 9</p><p>2.2.1 Species of Marijuana– – – – – – – – 10</p><p>2.2.1.1<br><i>Cannabis sativa- </i>– – – – – – – – 10</p><p>2.2.1.2 <i>Cannabis</i><br>Indica- – – – – – – – 11</p><p>2.2.1.3 <i>Cannabis</i><br>Ruderalis- – – – – – – – 12</p><p>2.3 <br>Economic Importance of Marijuana- – – – – – 15</p><p>2.4 <br>Constituents of <i>Cannabis</i>– – – – – – – – 17</p><p>2.4.1 Phytocannabinoids<br>— – – – – – – – 17</p><p>2.4.2 Classification- – – – – – – – – 18</p><p>2.4.3 Noncannabinoid-Type<br>Constituents- – – – – – 20</p><p>2.4.4 Hydrocarbons- – – – – – – – – 23</p><p>2.4.5 Nitrogen-Containing<br>Compounds – – – – 23</p><p>2.4.6 Carbohydrates- – – – – – – – – 24</p><p>2.4.7 Flavonoids- – – – – – – – – – 24</p><p>2.4.8 Fatty<br>Acids- – – – – – – – – – 25</p><p>2.4.9 Noncannabinoid<br>Phenols- – – – – – – 25</p><p>2.4.10 Other- – – – – – – – – – 26</p><p>2.4.11 Cannabinoid Receptor System- – – – – – 26</p><p>2.4.12 Cannabinoid 1 and 2 Receptors- – – – – – 27</p><p>2.5 Sex<br>Hormones and Its Synthesis- – – – – – 28</p><p>2.6 The<br>Protein Hormones- – – – – – – – 28</p><p>2.6.1 The<br>Gonadotropins- – – – – – – – 28</p><p>2.6.2 Luteinizing<br>Hormone (LH)- – – – – – – 29</p><p>2.6.3 Human<br>Chorionic Gonadotropin (hCG)- – – – – 30</p><p>2.6.4 Prolactin<br>(Prl)- – – – – – – – – 31</p><p>2.7 The<br>Steroid Hormones- – – – – – – – 32</p><p>2.7.1 Oestrogens- – – – – – – – – – 32</p><p>2.7.2 Oestradiol<br>(E2)- – – – – – – – – 32</p><p>2.7.3 Oestrone<br>(E1)- – – – – – – – – 33</p><p>2.7.4 Oestriol<br>(E3)- – – – – – – – – 33</p><p>2.7.5 Progesterone<br>(P4)- – – – – – – – – 34</p><p>2.7.6 Testosterone<br>(T)- – – – – – – – – 35</p><p>2.8 Cannabis<br>Effects- – – – – – – – – 35</p><p>2.8.1 Endocrine<br>effects – – – – – – – – 35</p><p>2.8.2 Hypothalamic Pituitary-Gonadal Axis – – – – – 35</p><p>2.9 Hpg Axis Effects In Males – – – – – – 37</p><p>2.9.1 Effects on Reproductive Hormones in Males – – – – 37</p><p>2.10 Effects on Prolactin – – – – – – – 39</p><p>2.10.1 Effects on other<br>Body Systems – – – – – 40</p><p>2.10.2 Vitamin C – – – – – – – – – 41</p><p>2.10.3 Biosynthesis and molecular structure of<br>vitamin C – – 43</p><p>2.10.4 Redox metabolism and antioxidant properties<br>of vitamin C- – 44</p>
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