Chapter ONE
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms
Chapter TWO
2.1 Overview of Liver Functions
2.2 Allium Ascalonicum Extracts
2.3 Liver Function Tests
2.4 Effects of Allium Ascalonicum on Liver Functions
2.5 Previous Studies on Allium Ascalonicum
2.6 Liver Function Disorders
2.7 Mechanism of Liver Function Regulation
2.8 Importance of Maintaining Healthy Liver Functions
2.9 Role of Liver in Detoxification
2.10 Summary of Literature Review
Chapter THREE
3.1 Research Methodology Overview
3.2 Selection of Adult Wistar Rats
3.3 Administration of Allium Ascalonicum Extract
3.4 Liver Function Tests Procedures
3.5 Data Collection and Analysis
3.6 Statistical Methods
3.7 Ethical Considerations
3.8 Research Timeline
Chapter FOUR
4.1 Analysis of Liver Function Test Results
4.2 Effects of Allium Ascalonicum Extract on ASP Levels
4.3 Effects of Allium Ascalonicum Extract on ALT Levels
4.4 Effects of Allium Ascalonicum Extract on AST Levels
4.5 Effects of Allium Ascalonicum Extract on Direct Bilirubin Levels
4.6 Effects of Allium Ascalonicum Extract on Total Bilirubin Levels
4.7 Comparison with Control Group
4.8 Discussion on Findings
Chapter FIVE
5.1 Conclusion and Summary
5.2 Summary of Findings
5.3 Implications of the Study
5.4 Recommendations for Future Research
5.5 Conclusion and Final Remarks
Project Abstract
The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).