Home / Biology edcuation / Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Antioxidants
2.2 Functions of Superoxide Dismutase
2.3 Role of Catalase in the Body
2.4 Importance of Malondialdehyde
2.5 Telferia Occidentalis in Antioxidant Activity
2.6 Vernonia Amygdalina and its Antioxidant Properties
2.7 Interactions Between Antioxidants and High Sucrose Diet
2.8 Effects of High Sucrose Diet on Antioxidant Levels
2.9 Previous Studies on Antioxidants and Diet
2.10 Current Understanding of Antioxidant Mechanisms

Chapter THREE

3.1 Research Design and Methodology
3.2 Selection of Animal Models
3.3 Administration of Telferia Occidentalis and Vernonia Amygdalina
3.4 High Sucrose Diet Feeding Protocol
3.5 Sample Collection and Analysis Procedures
3.6 Data Collection Methods
3.7 Statistical Analysis Techniques
3.8 Ethical Considerations in Animal Studies

Chapter FOUR

4.1 Analysis of Antioxidant Levels in Brain Tissue
4.2 Antioxidant Effects in Plasma
4.3 Antioxidant Activity in Liver Samples
4.4 Comparison of Antioxidant Levels Across Tissues
4.5 Impact of Telferia Occidentalis on Antioxidant Enzymes
4.6 Influence of Vernonia Amygdalina on Antioxidant Pathways
4.7 Malondialdehyde Levels in Different Tissues
4.8 Discussion on the Interplay of Antioxidants and Diet

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusions Drawn from the Study
5.3 Implications for Future Research
5.4 Recommendations for Practical Applications
5.5 Reflections on Research Process
5.6 Closing Remarks

Project Abstract

This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others were fed with normal rat chow. Antioxidant status were analysed in the brain, plasma and heart after four weeks of feeding. The result shows the imbalance caused by high sucrose diets having an effect on the antioxidants as the levels of superoxide dismutase, malondialdehyde and catalase in the liver, brain and plasma were significantly reduced (p<0.05). Therefore, moderate consumption of vegetable extracts can modulate antioxidant activity.

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