Cardio protective activities of n-hexane extract of desmodium velutinum stem on albino wister rat
Table Of Contents
Chapter ONE
1.1 Introduction1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms
Chapter TWO
2.1 Overview of Cardiovascular Diseases2.2 Desmodium Velutinum and its Medicinal Properties
2.3 Previous Research on N-Hexane Extracts
2.4 Mechanisms of Cardio Protection
2.5 Animal Models in Cardiovascular Research
2.6 Pharmacological Studies on Desmodium Velutinum
2.7 Comparative Studies with Other Plant Extracts
2.8 Clinical Trials and Observations
2.9 Challenges in Cardio Protective Research
2.10 Future Directions in Cardio Protection Research
Chapter THREE
3.1 Research Design and Rationale3.2 Selection of Study Participants
3.3 Data Collection Methods
3.4 Experimental Protocols
3.5 Data Analysis Techniques
3.6 Ethical Considerations
3.7 Validity and Reliability
3.8 Statistical Tools and Software
Chapter FOUR
4.1 Cardio Protective Effects of N-Hexane Extract4.2 Biochemical Analysis of Cardiac Parameters
4.3 Histological Examination of Cardiac Tissues
4.4 Inflammatory Markers in Cardio Protection
4.5 Oxidative Stress and Antioxidant Capacity
4.6 Molecular Pathways in Cardio Protection
4.7 Comparison with Standard Drugs
4.8 Interpretation of Results and Discussion
Chapter FIVE
5.1 Summary of Findings5.2 Conclusions
5.3 Implications for Clinical Practice
5.4 Recommendations for Future Research
5.5 Contributions to Cardio Protective Science
Project Abstract
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing 3.6g of the cow’s brain twice a day for seven days. Rats on group two was fed with only grower’s mash and water for seven days; rats in group three was later administered orally 2ml of dissolved vasoprin drug once in a day for 3 days.
Rats in group four were also administered orally 0.5ml of the liquid drug extract of Desmodium Velutinum stem once a day for 3 days. During these three (3) days, the rats were given grower’s mash and water. After the feeding period, the rate fed with the cow’s brain showed a significant increases in the activities of marker enzymes such as creatine kinase (CK), creatine kinase MB (CKMB), Aspartatatranseaminase (AST), Alaninetransminase (ALT), and lactatedehydrogenase. This study shows that N-hexane extract of Desmodium Velutinum stem posses cardio protective effect on albino wister rats than the known drug (vasoprin) if only one can increase the dosage of the extract for a period of time.
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