Assessment of the relationship between some trace elements and antioxidant enzymes in under-five children with protein- energy malnutrition
Table Of Contents
Chapter ONE
1.1 Introduction1.2 Background of study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms
Chapter TWO
2.1 Overview of Trace Elements2.2 Importance of Antioxidant Enzymes
2.3 Protein-Energy Malnutrition in Under-Five Children
2.4 Relationship Between Trace Elements and Antioxidant Enzymes
2.5 Previous Studies on Trace Elements and Antioxidant Enzymes
2.6 Effects of Deficiencies in Trace Elements and Antioxidant Enzymes
2.7 Role of Nutrition in Child Development
2.8 Factors Affecting Nutrient Absorption
2.9 Diagnostic Methods for Malnutrition
2.10 Nutritional Interventions for Protein-Energy Malnutrition
Chapter THREE
3.1 Research Methodology Overview3.2 Research Design
3.3 Population and Sample Selection
3.4 Data Collection Methods
3.5 Data Analysis Techniques
3.6 Ethical Considerations
3.7 Pilot Study
3.8 Validity and Reliability of Data
Chapter FOUR
4.1 Overview of Research Findings4.2 Analysis of Trace Elements Levels
4.3 Assessment of Antioxidant Enzymes Activity
4.4 Correlation Between Trace Elements and Antioxidant Enzymes
4.5 Comparison with Control Group
4.6 Discussion on Nutritional Implications
4.7 Implications for Public Health
4.8 Recommendations for Future Research
Chapter FIVE
5.1 Conclusion and Summary of Findings5.2 Revisiting Research Objectives
5.3 Contributions to Existing Knowledge
5.4 Practical Implications
5.5 Areas for Future Research
Project Abstract
Assessment of the relationship between some trace elements and antioxidant enzymes was carried out on 98 under-five children with protein-energy malnutrition (PEM) and 98 age- and sex-matched apparently healthy children (control). The malnourished children involve those with Marasmus, Kwashiorkor and Marasmic-kwashiorkor. Venous blood (2ml) was collected from both PEM children and control for biochemical analysis using standard methods. Results obtained show that mean serum total protein (55.76±3.95) and albumin (26.43±2.78) levels and superoxide dismutase (SOD) (1.87±0.32) and glutathione peroxidase (GPx) (42.38±5.03) activities in malnourished children were significantly lower.
Project Overview
INTRODUCTION
1.1 Background of the Study
Severe malnutrition is common among developing countries both in rural and urban areas (Psaki et al., 2012).It is responsible for at least half of the 7.6 million child‟sdeaths each year indeveloping countries (Park et al., 2012). Children who are poorly nourished suffer up to 160 days of illness each year (UNICEF, 2008). Malnutrition magnifies the effects of every disease, including measles and malaria. The estimated proportions of deaths in which malnutrition is an underlying cause are diarrhoea (61%), malaria (57%), pneumonia (52%) and measles (45%) (Black et al., 2003). Protein-energy malnutrition (PEM) is one of the most prevalent and devastating forms of malnutrition in the world (Whitney and Rolfes, 2008).
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