In the field of toxicology or environmental science, some researchers are wondering a question. That is, whether specific molecular signaling pathways in response to certain environmental toxicants or stresses exist in organisms. We selected three well-described response signals (heavy metal response, heat shock response, and hypoxia response) to discuss this question. So far, the obtained knowledge does not support the possible existence of specific molecular signaling pathways in response to certain environmental toxicants or stresses at least in nematodes.
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