Home / Biology edcuation / EPIDEMIOLOGICAL STUDIES AND MOLECULAR CHARACTERISATION OF DERMATOPHYTES AMONG ALMAJIRAI IN MAKARFI LOCAL GOVERNMENT AREA OF KADUNA STATE

EPIDEMIOLOGICAL STUDIES AND MOLECULAR CHARACTERISATION OF DERMATOPHYTES AMONG ALMAJIRAI IN MAKARFI LOCAL GOVERNMENT AREA OF KADUNA STATE

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Dermatophytes
2.2 Epidemiological Studies on Dermatophytes
2.3 Molecular Characterization Techniques
2.4 Almajirai Community in Nigeria
2.5 Dermatophyte Infections among Almajirai
2.6 Socioeconomic Factors Influencing Dermatophyte Transmission
2.7 Treatment and Control of Dermatophyte Infections
2.8 Global Perspectives on Dermatophyte Research
2.9 Emerging Trends in Dermatophyte Studies
2.10 Gaps in Current Literature

Chapter THREE

3.1 Research Design and Approach
3.2 Sampling Techniques
3.3 Data Collection Methods
3.4 Data Analysis Procedures
3.5 Ethical Considerations
3.6 Reliability and Validity
3.7 Research Limitations
3.8 Study Variables and Measurements

Chapter FOUR

4.1 Demographic Characteristics of Almajirai Participants
4.2 Prevalence of Dermatophyte Infections
4.3 Molecular Identification of Dermatophytes
4.4 Risk Factors for Dermatophyte Transmission
4.5 Treatment Patterns among Almajirai
4.6 Comparison with General Population
4.7 Discussion on Socioeconomic Impact
4.8 Recommendations for Future Interventions

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusions
5.3 Implications for Public Health
5.4 Recommendations for Policy and Practice
5.5 Areas for Future Research

Project Abstract

ABSTRACT

This study is undertaken to measure the variation of terrestrial gamma radiation and the

activity concentrations of U-238, Th-232 and K-40 in soil of Northern part of Zamfara State (Nigeria), and assess the potential health hazards associated with the exposures to the natural radiation in the area with respect to geological formations. Inspector AlertTM Nuclear Radiation Monitor and HPGe gamma ray spectrometer were used for TGRD and laboratory analyses respectively. The measured TGRD rates ranged from 20.00 to 61.43 nGy/h, with mean value of 31.99 nGy/h. The mean (range) activity concentrations of U-238, Th-232 and K-40 in the soil samples were 19.43 ± 2.23 (8.82 ± 0.95 to 44.22 ± 5.78) Bq/kg, 23.26 ± 8.43 (11.02 ± 1.03 to 43.96 ± 2.15) Bq/kg and 268.62 ± 39.03 (57.45 ± 2.88 to 527.36 ± 12.38) Bq/kg respectively. These results were compared with the world average values for specific activities (i.e. 33, 45 and 420 Bq/kg) for U-238, Th-232 and K-40 respectively, and were found to be less than the worldwide average. The highest TGRD rate and activity concentrations of U-238, Th-232 and K-40 were recorded in an area underlain by Older Granite formation, which are enriched with high contents of radioactive materials. The radiological hazards to the public in the studied area was assessed by estimating mean values of radium equivalent activity, external hazard index, and activity utilization index for the soil samples were found to be 71.674± 7.099 Bq/kg, 0.1936± 0.0192, and 0.4688± 0.0448 respectively.In addition, the mean values of absorbed gamma dose rates, annual outdoors effective dose rates, and excess lifetime cancer risk for both TGRD rate measurements and spectrometric analyses were found to be 31.99 nGy/h, 0.0393 mSv/y and 137.6x10-6, and 33.467



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