Home / Biochemistry / Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Liver Functions
2.2 Allium Ascalonicum - Properties and Uses
2.3 Liver Diseases and Their Impact
2.4 Previous Research on Allium Ascalonicum
2.5 Liver Enzymes: ASP, ALT, AST
2.6 Bilirubin: Direct and Total Levels
2.7 Mechanisms of Action of Allium Ascalonicum
2.8 Effects of Ethanol on Liver Functions
2.9 Ethanol Extracts in Traditional Medicine
2.10 Summary of Literature Review

Chapter THREE

3.1 Research Design and Methodology
3.2 Selection of Experimental Animals
3.3 Preparation of Allium Ascalonicum Ethanolic Extract
3.4 Dosage and Administration of Extract
3.5 Blood Sample Collection and Analysis
3.6 Statistical Analysis Methods
3.7 Ethical Considerations
3.8 Data Collection Procedures

Chapter FOUR

4.1 Analysis of Liver Function Test Results
4.2 Comparison with Control Group
4.3 Effects of Allium Ascalonicum Extract on Liver Enzymes
4.4 Impact on Bilirubin Levels
4.5 Interpretation of Findings
4.6 Discussion on Mechanisms of Action
4.7 Comparison with Previous Studies
4.8 Implications for Liver Health

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusions
5.3 Recommendations for Future Research
5.4 Practical Applications of Study
5.5 Final Thoughts

Project Abstract

The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).



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